Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RL451_RS00800 Genome accession   NZ_CP134617
Coordinates   126688..127311 (+) Length   207 a.a.
NCBI ID   WP_001045133.1    Uniprot ID   A0A0H2XHP5
Organism   Staphylococcus aureus strain IPLA16     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 121688..132311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL451_RS00780 (RL451_00780) - 122141..122536 (+) 396 WP_000901023.1 hypothetical protein -
  RL451_RS00785 (RL451_00785) fumC 122732..124117 (+) 1386 WP_000116231.1 class II fumarate hydratase -
  RL451_RS00790 (RL451_00790) - 124570..125391 (-) 822 WP_331385816.1 RluA family pseudouridine synthase -
  RL451_RS00795 (RL451_00795) - 125554..126666 (+) 1113 WP_000437968.1 GAF domain-containing sensor histidine kinase -
  RL451_RS00800 (RL451_00800) vraR 126688..127311 (+) 624 WP_001045133.1 response regulator Regulator
  RL451_RS00805 (RL451_00805) xdrA 127667..128131 (+) 465 WP_000375864.1 XRE family transcriptional regulator XdrA -
  RL451_RS00810 (RL451_00810) - 128310..129434 (+) 1125 WP_000992523.1 DUF445 domain-containing protein -
  RL451_RS00815 (RL451_00815) - 129503..129847 (+) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  RL451_RS00820 (RL451_00820) - 130340..130438 (+) 99 WP_001802255.1 hypothetical protein -
  RL451_RS00825 (RL451_00825) - 130729..131925 (+) 1197 WP_000238230.1 metallophosphoesterase family protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23895.56 Da        Isoelectric Point: 5.5730

>NTDB_id=806923 RL451_RS00800 WP_001045133.1 126688..127311(+) (vraR) [Staphylococcus aureus strain IPLA16]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=806923 RL451_RS00800 WP_001045133.1 126688..127311(+) (vraR) [Staphylococcus aureus strain IPLA16]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATTGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XHP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

100

0.406
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.377
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362