Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   P5708_RS02210 Genome accession   NZ_CP120563
Coordinates   454644..455768 (+) Length   374 a.a.
NCBI ID   WP_213848255.1    Uniprot ID   -
Organism   Escherichia coli strain H22     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 449644..460768
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5708_RS02185 (P5708_02185) mscL 449761..450174 (-) 414 WP_000022445.1 large-conductance mechanosensitive channel protein MscL -
  P5708_RS02190 (P5708_02190) trkA 450304..451680 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  P5708_RS02195 (P5708_02195) rsmB 451702..452991 (-) 1290 WP_000744767.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  P5708_RS02200 (P5708_02200) fmt 453043..453990 (-) 948 WP_000004421.1 methionyl-tRNA formyltransferase -
  P5708_RS02205 (P5708_02205) def 454005..454514 (-) 510 WP_000114984.1 peptide deformylase -
  P5708_RS02210 (P5708_02210) dprA 454644..455768 (+) 1125 WP_213848255.1 DNA-protecting protein DprA Machinery gene
  P5708_RS02215 (P5708_02215) smg 455740..456213 (+) 474 WP_001553514.1 DUF494 family protein Smg -
  P5708_RS02220 (P5708_02220) yrdD 456242..456784 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  P5708_RS02225 (P5708_02225) tsaC 456789..457361 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  P5708_RS02230 (P5708_02230) aroE 457366..458184 (+) 819 WP_001553512.1 shikimate dehydrogenase -
  P5708_RS02235 (P5708_02235) yrdB 458181..458438 (+) 258 WP_001070581.1 DUF1488 domain-containing protein -
  P5708_RS02240 (P5708_02240) yrdA 458414..458968 (-) 555 WP_122992030.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40900.82 Da        Isoelectric Point: 6.0395

>NTDB_id=806202 P5708_RS02210 WP_213848255.1 454644..455768(+) (dprA) [Escherichia coli strain H22]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGSHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=806202 P5708_RS02210 WP_213848255.1 454644..455768(+) (dprA) [Escherichia coli strain H22]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGCCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGTCTCACTGGTTAATAAA
ACAGGGGGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

49.677

82.888

0.412
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39