NTDB

Overview

Name	coiA	Type	Machinery gene
Locus tag	LLUC147_RS08690	Genome accession	NZ_CP120473
Coordinates	1736080..1737063 (-)	Length	327 a.a.
NCBI ID	WP_032950503.1	Uniprot ID	A0A1V0PIB8
Organism	Lactococcus cremoris strain UC147
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1731080..1742063

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC147_RS08675 (LLUC147_08715)	-	1732432..1733358 (-)	927	WP_134047427.1	peptidyl-prolyl cis-trans isomerase	-
LLUC147_RS08680 (LLUC147_08720)	-	1733514..1734197 (-)	684	WP_011676723.1	O-methyltransferase	-
LLUC147_RS08685 (LLUC147_08725)	pepF	1734200..1736005 (-)	1806	WP_081196818.1	oligoendopeptidase F	Regulator
LLUC147_RS08690 (LLUC147_08730)	coiA	1736080..1737063 (-)	984	WP_032950503.1	competence protein CoiA	Machinery gene
LLUC147_RS08695 (LLUC147_08735)	-	1737138..1738223 (-)	1086	WP_081196819.1	YdcF family protein	-
LLUC147_RS08700 (LLUC147_08740)	-	1738377..1738964 (-)	588	WP_014572239.1	alpha/beta hydrolase	-
LLUC147_RS08705 (LLUC147_08745)	-	1739003..1739200 (-)	198	WP_250638141.1	alpha/beta hydrolase	-
LLUC147_RS08710 (LLUC147_08750)	-	1739432..1740853 (-)	1422	WP_011676727.1	NCS2 family permease	-
LLUC147_RS08715 (LLUC147_08755)	-	1741160..1741996 (+)	837	WP_011676728.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

Download Length: 327 a.a. Molecular weight: 39121.86 Da Isoelectric Point: 9.7664

                                >NTDB_id=805788 LLUC147_RS08690 WP_032950503.1 1736080..1737063(-) (coiA) [Lactococcus cremoris strain UC147]

MLTAIDENNKIINLLELERKELTGKFYCPSCHAELLIKNGQIKVLHFAHKSLKSCNLWLENESEQHLGLKKILYQWFKRT

DKVEIERYLPELNQRPDLLVNDKIAIEIQCSHLSIKRLKERTENYKAHGFKVLWLMGKDLWLAEQVTKLQKNLVYFSENR

GFFYWELDFQRKKLRLKSLIHEDLRGRIICLQEEIPFGKGRLIAHLRLPYLAQKLVKIPTFKDPKLSSFIRQQLYYQSPK

WMKIQEKYYQKGENLLTKKFEGPYIAPLGLNLLESFTDEMTITTFTQIDQNVKLYYENFLINFQRNSLEMLYPPCFYAIM

GKQKKEK

Nucleotide

Download Length: 984 bp

                                >NTDB_id=805788 LLUC147_RS08690 WP_032950503.1 1736080..1737063(-) (coiA) [Lactococcus cremoris strain UC147]

ATGCTGACAGCAATTGATGAAAATAATAAAATAATAAACTTACTGGAATTAGAACGCAAAGAATTGACCGGGAAATTTTA

TTGTCCTTCTTGTCATGCAGAGCTACTTATTAAAAATGGGCAGATAAAAGTTCTTCATTTTGCCCATAAATCTCTAAAGA

GCTGCAATTTATGGTTGGAAAATGAGTCAGAACAGCATTTAGGTTTGAAAAAAATATTATATCAGTGGTTTAAAAGGACT

GACAAAGTCGAAATTGAACGCTATTTGCCCGAACTTAACCAAAGACCAGATTTATTAGTAAATGACAAAATCGCTATTGA

GATACAATGCTCTCATTTATCTATTAAGCGCCTCAAAGAACGTACAGAAAATTATAAGGCGCATGGCTTTAAAGTGCTTT

GGTTGATGGGAAAGGATTTATGGCTGGCTGAACAGGTGACAAAACTTCAAAAAAATTTAGTTTATTTCTCGGAAAATAGA

GGATTCTTTTATTGGGAGTTAGATTTTCAGAGGAAAAAATTAAGATTAAAATCTCTTATTCATGAGGATTTACGCGGCAG

AATCATTTGCTTACAAGAGGAAATTCCTTTTGGAAAAGGACGACTTATTGCGCATCTACGCTTACCTTATTTGGCGCAAA

AACTGGTGAAAATTCCTACTTTTAAAGATCCTAAACTTTCTAGTTTTATTCGTCAGCAATTATACTATCAATCACCAAAA

TGGATGAAAATTCAAGAAAAATATTATCAAAAAGGAGAAAATTTACTGACGAAAAAATTTGAAGGTCCATACATTGCTCC

ACTAGGTTTAAATTTACTAGAGAGTTTTACTGACGAAATGACGATCACAACTTTTACTCAGATTGATCAAAATGTTAAGC

TTTACTATGAAAATTTTTTAATAAATTTCCAAAGAAATAGCCTTGAAATGCTCTATCCTCCCTGTTTCTATGCTATAATG

GGAAAGCAGAAGAAGGAAAAATAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(1-254)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A1V0PIB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
coiA	Lactococcus lactis subsp. cremoris KW2	97.248	100	0.972
coiA	Streptococcus mitis NCTC 12261	44.444	99.083	0.44
coiA	Streptococcus pneumoniae TIGR4	43.21	99.083	0.428
coiA	Streptococcus pneumoniae Rx1	43.21	99.083	0.428
coiA	Streptococcus pneumoniae D39	43.21	99.083	0.428
coiA	Streptococcus pneumoniae R6	43.21	99.083	0.428

Detailed information NTG0805788