Detailed information NTG0800756

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3K41_RS09680
• Genome accession: NZ_CP119713
• Coordinates: 1976723..1977766 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CUVET17-948
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1971723..1982766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3K41_RS09650 (P3K41_09625)	-	1972144..1973400 (-)	1257	WP_074347694.1	aminopeptidase	-
P3K41_RS09655 (P3K41_09630)	-	1973403..1973603 (-)	201	WP_000180460.1	DUF1128 family protein	-
P3K41_RS09660 (P3K41_09635)	-	1973750..1974214 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
P3K41_RS09665 (P3K41_09640)	-	1974221..1974496 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
P3K41_RS09670 (P3K41_09645)	-	1974774..1975991 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
P3K41_RS09675 (P3K41_09650)	vraR	1976104..1976733 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
P3K41_RS09680 (P3K41_09655)	vraS	1976723..1977766 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
P3K41_RS09685 (P3K41_09660)	liaF	1977763..1978464 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
P3K41_RS09690 (P3K41_09665)	-	1978479..1978865 (-)	387	WP_001110182.1	hypothetical protein	-
P3K41_RS09695 (P3K41_09670)	map	1979082..1979840 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
P3K41_RS09700 (P3K41_09675)	-	1980424..1981410 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
P3K41_RS09705 (P3K41_09680)	-	1981599..1982012 (-)	414	WP_025174370.1	hypothetical protein	-
P3K41_RS09710 (P3K41_09685)	-	1982041..1982151 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=800756 P3K41_RS09680 WP_001017131.1 1976723..1977766(-) (vraS) [Staphylococcus aureus strain CUVET17-948]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=800756 P3K41_RS09680 WP_001017131.1 1976723..1977766(-) (vraS) [Staphylococcus aureus strain CUVET17-948]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1