Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   PY824_RS08395 Genome accession   NZ_CP119172
Coordinates   1609471..1610823 (-) Length   450 a.a.
NCBI ID   WP_014295009.1    Uniprot ID   -
Organism   Streptococcus macedonicus strain SGM CIP105683     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1604471..1615823
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY824_RS08380 (PY824_08380) rnc 1606051..1606737 (-) 687 WP_014295006.1 ribonuclease III -
  PY824_RS08385 (PY824_08385) - 1607007..1608263 (+) 1257 WP_115265893.1 ISL3 family transposase -
  PY824_RS08390 (PY824_08390) vicX 1608661..1609470 (-) 810 WP_115265894.1 MBL fold metallo-hydrolase Regulator
  PY824_RS08395 (PY824_08395) vicK 1609471..1610823 (-) 1353 WP_014295009.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PY824_RS08400 (PY824_08400) vicR 1610816..1611526 (-) 711 WP_014295010.1 response regulator YycF Regulator
  PY824_RS08405 (PY824_08405) - 1611831..1612595 (+) 765 WP_014295011.1 amino acid ABC transporter ATP-binding protein -
  PY824_RS08410 (PY824_08410) - 1612606..1613418 (+) 813 WP_014295012.1 transporter substrate-binding domain-containing protein -
  PY824_RS08415 (PY824_08415) - 1613435..1614139 (+) 705 WP_039671116.1 amino acid ABC transporter permease -
  PY824_RS08420 (PY824_08420) - 1614151..1614798 (+) 648 WP_014295014.1 amino acid ABC transporter permease -
  PY824_RS08425 (PY824_08425) - 1614890..1615498 (-) 609 WP_115265895.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51553.66 Da        Isoelectric Point: 4.7361

>NTDB_id=798062 PY824_RS08395 WP_014295009.1 1609471..1610823(-) (vicK) [Streptococcus macedonicus strain SGM CIP105683]
MNDTMLQNLTYFEQAILFLLAFVAVYFVYLAIREYQTSANIRRLSGKVRELITGKYTEDIIIEKDRDLAELADQLNDLSK
VFRLAQENLAQEKNRLASILSYMTDGVLATDRAGNIIMINQTAQQQLNLEREEALQMNIVDILGSDSTYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPNFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTISGKQYEIVRNYPIKP
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSEIYDEWEDEEE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=798062 PY824_RS08395 WP_014295009.1 1609471..1610823(-) (vicK) [Streptococcus macedonicus strain SGM CIP105683]
ATGAATGATACAATGTTACAAAATTTAACTTATTTTGAACAAGCCATTCTCTTTCTTTTAGCATTTGTCGCAGTTTATTT
TGTTTATTTAGCGATAAGAGAATATCAAACTTCTGCTAATATTCGCCGTTTGAGTGGTAAAGTGCGAGAGCTTATCACAG
GAAAATACACAGAAGATATTATTATTGAAAAAGATAGAGACTTAGCTGAGTTAGCTGATCAATTAAATGATTTGTCAAAA
GTCTTTCGTTTAGCGCAGGAAAATTTGGCACAAGAAAAGAATCGTTTGGCGAGTATCTTATCTTATATGACAGACGGTGT
CTTGGCGACTGACCGTGCTGGAAATATCATAATGATAAATCAGACCGCGCAACAACAACTCAATTTAGAGCGTGAAGAAG
CTTTGCAGATGAATATTGTTGATATTTTGGGTTCTGATAGCACTTATAGTTATCATGATTTGGTGTCAAAAACACCTGAA
ATTGTCTTGAACCGTCGTGACGAAACAGGTGAATTTATCACTTTACGTATTCGCTTTGCTCTAAATCGTCGTGATAGTGG
TTTTATTTCAGGGTTGATTGCCGTTTTGCATGACACAACCGAACAAGAGAAAGAAGACCGTGAGCGTCGTCTTTTCGTTT
CTAACGTTAGTCATGAATTGCGAACACCATTAACATCTGTAAAATCTTATCTGGAAGCCTTAGATGAAGGAGCGCTCAAA
GAAGACATTGCGCCAAATTTTATCAAAGTATCTTTAGATGAAACAAACCGCATGATTCGTATGATTTCAGACTTGCTTAA
TTTATCGCGTATTGATAATCAGACGGTTCAATTGGAAGTGGAAATGACAAATTTCACAGCATTTATGACATCAATTCTTA
ACCGTTTTGATCAAATTAAAAGCCAACATACAATCAGCGGAAAACAGTATGAGATTGTCAGGAATTATCCTATTAAACCA
ATCTGGCTTGAAATTGATCCTGATAAGATGACGCAGGTTTTGGATAATATCCTTAATAATGCTATCAAATATTCACCAGA
TGGTGGAAAAATCACAGTTAGCATGAAAACGACGGAAACACAGTTGATTATCTCAATCTCTGATGAAGGGCTTGGTATTC
CTAAGAAAGATTTGCCATTGATTTTCGACCGTTTCTACCGTGTGGATAAGGCTCGAAGTCGTGCCCAAGGTGGTTCAGGA
CTTGGCTTAGCTATCGCAAAAGAAATTGTCAAACAACATAAAGGTTTTATTTGGGCACAAAGTACTTACGGAAAAGGGTC
GACCTTTACGATTGTACTTCCTTACGAAAAAGATTCTGAAATTTATGATGAATGGGAGGATGAAGAAGAGTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-189)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.94

92.222

0.691
  micB Streptococcus pneumoniae Cp1015

65.566

94.222

0.618