Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   PY824_RS05760 Genome accession   NZ_CP119172
Coordinates   1070357..1071697 (-) Length   446 a.a.
NCBI ID   WP_039670832.1    Uniprot ID   A0A081JHE3
Organism   Streptococcus macedonicus strain SGM CIP105683     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1065357..1076697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY824_RS05735 (PY824_05735) - 1065861..1066925 (-) 1065 WP_014294579.1 BMP family protein -
  PY824_RS05740 (PY824_05740) deoC 1067114..1067776 (-) 663 WP_014294580.1 deoxyribose-phosphate aldolase -
  PY824_RS05745 (PY824_05745) - 1068267..1068860 (-) 594 WP_014294582.1 class I SAM-dependent methyltransferase -
  PY824_RS05750 (PY824_05750) coaA 1068974..1069894 (+) 921 WP_014294583.1 type I pantothenate kinase -
  PY824_RS05755 (PY824_05755) rpsT 1069969..1070220 (+) 252 WP_081498578.1 30S ribosomal protein S20 -
  PY824_RS05760 (PY824_05760) ciaH 1070357..1071697 (-) 1341 WP_039670832.1 cell wall metabolism sensor histidine kinase WalK Regulator
  PY824_RS05765 (PY824_05765) ciaR 1071687..1072361 (-) 675 WP_014294586.1 response regulator transcription factor Regulator
  PY824_RS05770 (PY824_05770) - 1072559..1075102 (-) 2544 WP_039670833.1 M1 family metallopeptidase -
  PY824_RS05775 (PY824_05775) - 1075403..1076659 (+) 1257 WP_039670834.1 ISL3 family transposase -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50231.14 Da        Isoelectric Point: 6.2742

>NTDB_id=798051 PY824_RS05760 WP_039670832.1 1070357..1071697(-) (ciaH) [Streptococcus macedonicus strain SGM CIP105683]
MLNKLQKKLSSGTFSHFFHFFAVFTGIFVIMTVIILQIMRYGLYSSVDTSLQNAADNANDYVVRTMERSDTLQSNDSPTD
TFSGGTSSSGKAKPSTSRVGLSNVSVLLYDEDGKILNALDAFVQFGTLSTTFDEGSVGEIKEQKITTIFGQTEKYHVLTV
KVSSSEYPSIKYATFLVSVRQLDEASERYVTITITVMVIFWIISVVASVYLANWTRKPIMESYEKQKTFVENASHELRTP
LTVLQNRLESLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEDIQPPTFNEIFENYDMIAEENG
KTFVGHNLVDRPIKSDRTLLKQLMTILFDNAIKYTDNDGVIEFTVKTTDKQTILTVADNGPGISDADKVKIFDRFYRVDK
ARTRQKGGFGLGLSLAKQIVDVLKGDIQVKDNQPKGTIFEVRFNRH

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=798051 PY824_RS05760 WP_039670832.1 1070357..1071697(-) (ciaH) [Streptococcus macedonicus strain SGM CIP105683]
ATGTTGAATAAATTACAGAAAAAATTATCATCAGGGACATTTTCACATTTCTTCCATTTCTTTGCTGTCTTCACGGGAAT
TTTTGTCATCATGACAGTTATCATTTTGCAGATTATGCGCTATGGTCTTTATTCCTCTGTTGATACGAGTTTGCAAAATG
CAGCAGACAATGCCAATGATTATGTCGTGCGAACTATGGAACGTAGCGATACTTTGCAATCGAATGATTCTCCTACGGAC
ACTTTTTCAGGAGGAACAAGTAGTTCTGGGAAAGCGAAACCTAGTACCAGCAGAGTTGGTCTAAGTAACGTTAGCGTTCT
TCTTTATGATGAAGACGGTAAAATCTTAAATGCTTTGGATGCTTTTGTTCAATTTGGAACGTTATCGACAACTTTTGATG
AAGGTAGTGTCGGCGAAATCAAAGAACAGAAGATTACGACCATTTTTGGTCAAACCGAGAAATACCATGTGCTGACTGTA
AAAGTGAGTAGTAGCGAGTATCCTAGTATAAAATACGCTACTTTCCTTGTTAGTGTTCGTCAGTTAGATGAAGCTAGCGA
ACGATATGTAACAATTACGATCACTGTTATGGTTATTTTCTGGATTATTTCGGTCGTAGCAAGTGTTTATCTTGCCAATT
GGACAAGAAAACCAATTATGGAAAGCTATGAAAAACAAAAAACCTTTGTCGAAAATGCTAGTCATGAGTTGCGTACACCG
CTTACTGTTTTGCAGAATCGTTTAGAAAGTCTCTTTAGGCGACCTGATGCTACAATTTTGGATAATAGTGAAAGTATTGC
CGCCAGTTTAGACGAAGTTCGAAATATGCGAATTTTGACCACAAATCTGCTGAATTTGGCACGTCGTGATGATGGTTTGA
AAGTTGAGTTGGAGGATATTCAACCACCGACTTTCAATGAAATCTTTGAAAATTACGATATGATTGCTGAAGAAAATGGC
AAGACATTTGTCGGACATAATTTGGTAGACCGACCAATCAAATCAGATCGTACATTGTTAAAACAACTGATGACTATCTT
ATTTGATAATGCCATAAAATACACCGACAATGATGGTGTCATTGAATTTACCGTTAAAACAACAGACAAACAAACAATTC
TGACAGTTGCTGATAACGGTCCAGGAATTAGCGACGCTGATAAAGTTAAGATTTTTGACCGTTTTTATCGTGTGGATAAA
GCACGGACACGTCAAAAAGGCGGTTTTGGTCTAGGATTGTCACTTGCTAAGCAAATTGTTGACGTTTTAAAAGGCGATAT
TCAAGTCAAAGATAACCAACCAAAAGGAACTATTTTTGAAGTCCGTTTTAATCGTCATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(227-292)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A081JHE3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.045

99.327

0.596
  ciaH Streptococcus pneumoniae Rx1

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae D39

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae R6

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.467

99.327

0.511