Detailed information NTG0795940

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYH53_RS09585
• Genome accession: NZ_CP118860
• Coordinates: 1938828..1939871 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 7075
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1933828..1944871

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH53_RS09555 (PYH53_09555)	-	1934250..1935506 (-)	1257	WP_072398252.1	aminopeptidase	-
PYH53_RS09560 (PYH53_09560)	-	1935509..1935709 (-)	201	WP_000180460.1	DUF1128 family protein	-
PYH53_RS09565 (PYH53_09565)	-	1935856..1936320 (+)	465	WP_000567539.1	low molecular weight protein-tyrosine-phosphatase	-
PYH53_RS09570 (PYH53_09570)	-	1936327..1936602 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
PYH53_RS09575 (PYH53_09575)	-	1936880..1938097 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
PYH53_RS09580 (PYH53_09580)	vraR	1938209..1938838 (-)	630	WP_000153532.1	two-component system response regulator VraR	Regulator
PYH53_RS09585 (PYH53_09585)	vraS	1938828..1939871 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
PYH53_RS09590 (PYH53_09590)	liaF	1939868..1940569 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
PYH53_RS09595 (PYH53_09595)	-	1940584..1940970 (-)	387	WP_001110179.1	hypothetical protein	-
PYH53_RS09600 (PYH53_09600)	map	1941187..1941945 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
PYH53_RS09605 (PYH53_09605)	-	1942417..1943403 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
PYH53_RS09610 (PYH53_09610)	-	1943834..1944247 (-)	414	WP_025175030.1	hypothetical protein	-
PYH53_RS09615 (PYH53_09615)	-	1944276..1944386 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=795940 PYH53_RS09585 WP_001017131.1 1938828..1939871(-) (vraS) [Staphylococcus aureus strain 7075]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=795940 PYH53_RS09585 WP_001017131.1 1938828..1939871(-) (vraS) [Staphylococcus aureus strain 7075]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTGAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1