Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   PW220_RS05865 Genome accession   NZ_CP118734
Coordinates   1170063..1171445 (-) Length   460 a.a.
NCBI ID   WP_248055191.1    Uniprot ID   A0AA97AB82
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1165063..1176445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS05840 (PW220_05845) - 1165412..1166689 (-) 1278 WP_105117938.1 pyrimidine-nucleoside phosphorylase -
  PW220_RS05845 (PW220_05850) - 1166686..1167276 (-) 591 WP_105117939.1 class I SAM-dependent methyltransferase -
  PW220_RS05850 (PW220_05855) coaA 1167389..1168309 (+) 921 WP_105114818.1 type I pantothenate kinase -
  PW220_RS05855 (PW220_05860) rpsT 1168368..1168616 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  PW220_RS05860 (PW220_05865) - 1168663..1169892 (-) 1230 WP_248055192.1 transglutaminase domain-containing protein -
  PW220_RS05865 (PW220_05870) ciaH 1170063..1171445 (-) 1383 WP_248055191.1 sensor histidine kinase Regulator
  PW220_RS05870 (PW220_05875) ciaR 1171438..1172109 (-) 672 WP_105117942.1 response regulator transcription factor Regulator
  PW220_RS05875 (PW220_05880) - 1172251..1172679 (-) 429 WP_248055189.1 hypothetical protein -
  PW220_RS05880 (PW220_05885) phoU 1172826..1173482 (-) 657 WP_105117944.1 phosphate signaling complex protein PhoU -
  PW220_RS05885 (PW220_05890) pstB 1173510..1174268 (-) 759 WP_171998850.1 phosphate ABC transporter ATP-binding protein PstB -
  PW220_RS05890 (PW220_05895) pstB 1174280..1175083 (-) 804 WP_172091490.1 phosphate ABC transporter ATP-binding protein PstB -
  PW220_RS05895 (PW220_05900) pstA 1175108..1175995 (-) 888 WP_044758719.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 460 a.a.        Molecular weight: 52047.50 Da        Isoelectric Point: 6.3267

>NTDB_id=794694 PW220_RS05865 WP_248055191.1 1170063..1171445(-) (ciaH) [Streptococcus iners subsp. hyiners strain 29892]
MFKRYKKIVNTESFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQTTDDTLSRIKDEPSMMIGFAIARTYEPDSEFIIHD
EGEQPSATNSSSTTASSEDPQPKDKKGDQPMRLGTNTHVLLYSKSGALLNPDNFTGLSDLKVDKEKLGEIKELTVETPFG
SEEHYRYITVELSAEDLGYYSNYDITCATILVNVSQIKSSIGTYESTVAVVMISAWLISIVASIYLANLSMKPILISYQK
QKDFVENASHELRTPLAVLQNRLESLFRHPEATILDSSESIGSSLEEVRNMRLLTTNLLNLARRDDGFKLDMVEVSPAYL
DEVFENYRIIAEENGKKFKCNNLIQKSFRTDRVLLKQLLTILFDNAMKYTDENGDIHITATMKERHVSIAVADNGLGISD
ADKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKSLNGQILVKDNQPKGSIFEVHLPK

Nucleotide


Download         Length: 1383 bp        

>NTDB_id=794694 PW220_RS05865 WP_248055191.1 1170063..1171445(-) (ciaH) [Streptococcus iners subsp. hyiners strain 29892]
ATGTTTAAGAGATATAAAAAGATTGTCAATACGGAAAGTTTTTCCTTCTTTATTCGCTATTTTGCTGTATTTACCCTGAT
ATTTGGTTTGATGACAGCCATCATCTTTCAGCTCATGCGCTCCACTATGTATCAGACGACAGATGATACACTAAGTCGGA
TTAAGGATGAACCCTCTATGATGATTGGTTTTGCAATTGCGCGGACCTATGAGCCAGATTCTGAATTTATTATCCATGAT
GAAGGTGAGCAACCTTCTGCAACAAATTCCTCTTCAACTACTGCTTCATCGGAGGATCCACAACCAAAGGATAAGAAAGG
TGATCAACCAATGAGGTTGGGCACCAATACCCATGTTTTGCTCTACAGCAAGAGTGGTGCGCTTTTGAACCCAGATAATT
TTACAGGTTTATCCGATTTGAAAGTCGATAAAGAAAAGTTGGGGGAAATCAAGGAGTTGACGGTTGAAACTCCATTTGGT
TCCGAGGAACATTACCGTTATATCACGGTTGAATTATCCGCAGAGGATTTGGGCTATTATTCTAACTATGATATTACCTG
CGCAACGATTTTGGTCAATGTCAGTCAGATAAAGTCTTCTATTGGAACTTATGAATCAACCGTAGCTGTAGTTATGATTT
CAGCTTGGTTGATTTCGATTGTCGCTAGTATTTACTTGGCTAATCTCAGCATGAAACCAATTTTAATTAGCTATCAAAAG
CAAAAGGATTTTGTTGAGAATGCTAGCCACGAATTGCGTACACCACTAGCAGTATTGCAAAATCGCTTGGAAAGTCTATT
CCGTCATCCAGAAGCAACGATTTTGGACAGTAGTGAGAGTATTGGTTCTAGTCTGGAAGAAGTACGAAATATGCGCCTAC
TGACGACCAATCTGCTCAATCTTGCTCGGCGTGATGATGGATTTAAGCTAGATATGGTAGAGGTGAGCCCTGCCTACTTG
GATGAAGTGTTTGAAAACTACCGTATCATTGCTGAGGAAAATGGCAAGAAATTTAAGTGTAACAATCTCATTCAAAAGTC
CTTCCGAACGGACAGGGTTCTGTTGAAGCAATTATTAACGATATTATTTGATAATGCAATGAAATACACGGATGAGAATG
GTGACATTCACATTACGGCTACTATGAAGGAGCGCCATGTTTCCATCGCTGTAGCTGATAATGGTCTAGGTATCTCAGAT
GCAGATAAGAAGAAAATATTTGACCGCTTTTATAGGGTTGATAAGGCACGGACACGCCAAAAAGGTGGTTTTGGTCTGGG
ACTTTCTTTGGCTCAACAGATTATCAAATCCCTCAATGGTCAAATTCTTGTCAAAGATAATCAACCAAAAGGGAGTATTT
TTGAAGTTCATCTTCCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(241-307)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(351-459)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

49.673

99.783

0.496
  ciaH Streptococcus pneumoniae Rx1

49.455

99.783

0.493
  ciaH Streptococcus pneumoniae D39

49.455

99.783

0.493
  ciaH Streptococcus pneumoniae R6

49.455

99.783

0.493
  ciaH Streptococcus pneumoniae TIGR4

49.455

99.783

0.493