Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   PW220_RS03430 Genome accession   NZ_CP118734
Coordinates   666035..668272 (+) Length   745 a.a.
NCBI ID   WP_248054595.1    Uniprot ID   A0AA96VHT2
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 661035..673272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS03400 (PW220_03400) serC 661599..662690 (+) 1092 WP_105117396.1 3-phosphoserine/phosphohydroxythreonine transaminase -
  PW220_RS03405 (PW220_03405) - 662690..663247 (+) 558 WP_248054600.1 GNAT family N-acetyltransferase -
  PW220_RS03410 (PW220_03410) - 663300..664481 (+) 1182 WP_248054599.1 3-phosphoglycerate dehydrogenase family protein -
  PW220_RS03415 (PW220_03415) - 664484..664978 (+) 495 WP_248054598.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
  PW220_RS03420 (PW220_03420) - 664975..665328 (+) 354 WP_172050191.1 arsenate reductase family protein -
  PW220_RS03425 (PW220_03425) - 665377..666051 (+) 675 WP_248054597.1 helix-hairpin-helix domain-containing protein -
  PW220_RS03430 (PW220_03430) comEC/celB 666035..668272 (+) 2238 WP_248054595.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83884.89 Da        Isoelectric Point: 7.4197

>NTDB_id=794691 PW220_RS03430 WP_248054595.1 666035..668272(+) (comEC/celB) [Streptococcus iners subsp. hyiners strain 29892]
MSRLTKLPCQPIHLALLAVVAYFVVHSFSLLTMGLLSLLLVVFGVQQGKTVFLKTLPLLALFGLFFGCQKFQWEGAAQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQTYFQKLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSTWRRQALVYVKINFSAPMSHHMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVTVFVCLLML
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESFSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPLVKITWVNGFFVLMEKVIVWVADLGFRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVADIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEEWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPMFDAYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIKAYPRLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVKE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=794691 PW220_RS03430 WP_248054595.1 666035..668272(+) (comEC/celB) [Streptococcus iners subsp. hyiners strain 29892]
ATGTCACGGTTGACTAAGCTACCCTGCCAGCCCATCCACTTGGCTCTTTTGGCGGTGGTAGCCTACTTTGTAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGTTGAGTTTGTTACTAGTTGTCTTTGGTGTTCAGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAGCCCTGTTTGGACTGTTTTTCGGATGTCAAAAGTTTCAATGGGAGGGGGCAGCCCAGTCAGCC
CCGGAGCAAGTCACCACTGTGCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGCCTGTCCTTCCGCGGTCGGGC
TGACGGACAAACCTATCAAGTTTTCTACAAATTAGCCAGTCAGGAGGAACAGACCTATTTTCAAAAGCTGGCAGACCTGG
TCCAACTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCAGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCTTATCTG
AAAACACAAGGAATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGCTGTCAACTTGGCGGAGGCAAGCCTTGGTCTATGTCAAAATCAATTTTTCGGCTCCCATGAGCCACCACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCAGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGTTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAAC
AGTGGATAAGTTGCAGATTCCCTTTTCCCTGGTCTATGCTGGTTTGACAGGCTTTTCTGTGTCAGTGGTGCGGTCCTTGG
TCCAGAAAATTCTGGGCAATATGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACGGTCTTTGTCTGCCTGTTGATGCTG
CCCCGATTTTTACTGACGGCAGGTGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGTTTCAGTATTTCGCTGGGGATTTTGCCAGTGCTTATGACCTATTTCTATG
CCTTTCAGCCCCTGTCTATCCTCTTGACATTTGCCTTTTCCTTTGTCTTTGATGTCCTACTCTTGCCAGGCTTGTCGGTC
ATTTTTCTTTTGTCGCCTCTGGTCAAGATTACCTGGGTCAACGGATTTTTCGTCTTGATGGAAAAAGTCATTGTCTGGGT
AGCTGATTTGGGTTTCAGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGCGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATAGATGTGGGCGGACGAGTCGATTTTGCGGCCAAGGAGGAGTGGCAGGAGCGATCTTCGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCACAGTCGGGGCGTGGATAGGATTGATAGTCTAGTGCTGACCCACACCGACACAGAC
CATGTGGGCGATGTGCTGGAAGTAGCTAAGCAGGTTCAGATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTACC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTGCCGATGTTTGACG
CCTATCTAGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGATTCCATTGTTCTCTACGGTCGCTTGCTG
GAAACCAATTTTCTCTTTACAGGGGACTTGGAGCAAGGGGAGCTGGACTTGATAAAAGCTTATCCGCGACTACCTGTCGA
TGTCCTCAAAGCTGGTCACCATGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCCC
TGGTATCAGCTGGGGAAAACAATCGTTACAAGCATCCACACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGTACCGATCAGCAAGGAGCTATTCGATTCAGAGGCTGGAAGGAGTGGAGGATTGAGACGGTGAAGGAGTAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(215-461)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Domain of unknown function (DUF4131) (DUF4131)

(30-175)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.451

99.195

0.53
  comEC/celB Streptococcus mitis NCTC 12261

52.725

98.523

0.519
  comEC/celB Streptococcus pneumoniae TIGR4

51.565

98.658

0.509
  comEC/celB Streptococcus pneumoniae Rx1

51.293

98.658

0.506
  comEC/celB Streptococcus pneumoniae D39

51.293

98.658

0.506
  comEC/celB Streptococcus pneumoniae R6

51.293

98.658

0.506
  comEC Lactococcus lactis subsp. cremoris KW2

48.336

100

0.487