Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   PW220_RS02480 Genome accession   NZ_CP118734
Coordinates   458699..459343 (-) Length   214 a.a.
NCBI ID   WP_105133755.1    Uniprot ID   A0AA96VQV7
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 453699..464343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS02455 (PW220_02455) - 453737..454378 (+) 642 WP_248055979.1 YutD family protein -
  PW220_RS02460 (PW220_02460) rlmN 454387..455499 (+) 1113 WP_105118431.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  PW220_RS02465 (PW220_02465) - 455496..456023 (+) 528 WP_105118430.1 VanZ family protein -
  PW220_RS02470 (PW220_02470) nadE 456348..457172 (-) 825 WP_248055978.1 ammonia-dependent NAD(+) synthetase -
  PW220_RS02475 (PW220_02475) - 457185..458645 (-) 1461 WP_248055977.1 nicotinate phosphoribosyltransferase -
  PW220_RS02480 (PW220_02480) cclA/cilC 458699..459343 (-) 645 WP_105133755.1 prepilin peptidase Machinery gene
  PW220_RS02485 (PW220_02485) - 459397..460215 (-) 819 WP_105113376.1 cation diffusion facilitator family transporter -
  PW220_RS02490 (PW220_02490) - 460337..460855 (+) 519 WP_024409521.1 TetR/AcrR family transcriptional regulator -
  PW220_RS02495 (PW220_02495) - 460865..461419 (+) 555 WP_029177606.1 class I SAM-dependent methyltransferase -
  PW220_RS02500 (PW220_02500) - 461468..462724 (-) 1257 WP_192873108.1 ISL3 family transposase -
  PW220_RS02505 (PW220_02505) - 462858..463637 (-) 780 WP_248054787.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24334.42 Da        Isoelectric Point: 8.7028

>NTDB_id=794683 PW220_RS02480 WP_105133755.1 458699..459343(-) (cclA/cilC) [Streptococcus iners subsp. hyiners strain 29892]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPSSHCNACKRRLKAWDLIPILSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LLVLLCHFHILSIAETILILAGLVLTIYDIKHQEYPFAVWLLFTFVALILSQLNWLFCGFLVLAYLTEKWQLNIGSGDFL
YLASLSLLFGFTEIIWIIQLSSILGLAIFFIFKPKSLPYVPFLFLASLIINITL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=794683 PW220_RS02480 WP_105133755.1 458699..459343(-) (cclA/cilC) [Streptococcus iners subsp. hyiners strain 29892]
ATGAAGACAATTATCCTATTTTTCCTGGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
ATCCATTATCGCCCCATCTAGTCACTGCAATGCCTGCAAACGACGGCTCAAGGCTTGGGATCTAATTCCTATTCTTTCCC
AGCTTTCCACAAAATCTAAGTGCCGTTACTGCAAGGCGAAAATTCCTTATTGGTATCTGGGACTGGAATTCTTAGCTGGT
CTATTGGTCCTGCTCTGCCATTTTCACATCCTATCCATAGCTGAAACTATTCTTATCTTAGCCGGGCTGGTCTTGACCAT
TTACGACATCAAGCATCAGGAATATCCCTTCGCTGTCTGGCTACTCTTTACCTTTGTAGCCCTCATTCTCTCCCAGCTCA
ACTGGCTCTTCTGTGGCTTTTTGGTCCTGGCCTATCTGACTGAAAAATGGCAACTCAATATCGGTTCTGGCGATTTTCTC
TATCTGGCCAGCCTCTCACTCCTTTTCGGCTTTACAGAAATTATCTGGATTATTCAACTAAGTTCCATCCTAGGGCTGGC
CATCTTTTTCATCTTTAAACCCAAATCCCTACCCTATGTACCTTTTCTATTCCTTGCCAGCCTAATCATCAATATCACTC
TCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.289

98.598

0.486
  cclA/cilC Streptococcus pneumoniae Rx1

48.78

95.794

0.467
  cclA/cilC Streptococcus pneumoniae D39

48.78

95.794

0.467
  cclA/cilC Streptococcus pneumoniae R6

48.78

95.794

0.467
  cclA/cilC Streptococcus mitis NCTC 12261

46.919

98.598

0.463
  cclA/cilC Streptococcus pneumoniae TIGR4

47.805

95.794

0.458