Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   PW220_RS00310 Genome accession   NZ_CP118734
Coordinates   51836..52750 (+) Length   304 a.a.
NCBI ID   WP_248054888.1    Uniprot ID   A0AA96VG56
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 46836..57750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS00290 (PW220_00290) purB 47022..48314 (+) 1293 WP_248054881.1 adenylosuccinate lyase -
  PW220_RS00295 (PW220_00295) - 48592..49860 (+) 1269 WP_248054882.1 MerR family transcriptional regulator -
  PW220_RS00300 (PW220_00300) ruvB 50055..51053 (+) 999 WP_248054884.1 Holliday junction branch migration DNA helicase RuvB -
  PW220_RS00305 (PW220_00305) - 51120..51734 (+) 615 WP_248054885.1 HAD-IA family hydrolase -
  PW220_RS00310 (PW220_00310) comR 51836..52750 (+) 915 WP_248054888.1 helix-turn-helix domain-containing protein Regulator
  PW220_RS00315 (PW220_00315) - 52944..54179 (+) 1236 WP_248054889.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  PW220_RS00320 (PW220_00320) - 54369..55883 (+) 1515 WP_248054892.1 quinol oxidase -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 35988.02 Da        Isoelectric Point: 4.7473

>NTDB_id=794657 PW220_RS00310 WP_248054888.1 51836..52750(+) (comR) [Streptococcus iners subsp. hyiners strain 29892]
MNDKGFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTLSKIQYIANRLGMSLYELMPDYVKLPNRYLKLK
FEVLRTPTYENEELMDKRNQLMEEIYDNYYDDLPEEEQVAIDAFQSFVDIYETKSVHFGKEILDDYFEQVHRKDKFTVND
LLIIRLYLEHLQDEDVHSQSFQHFLDITRHFPTQMEVIDSNELFILRDVMLAAIGVLGSKQSFDYIPPIFATLDQLMVQT
HDFQKKPILNLLKWKYELYVNDDKQAAQQLYQEAVMFAKLIGDNHLVAKLEKAWVEEYNGIAKK

Nucleotide


Download         Length: 915 bp        

>NTDB_id=794657 PW220_RS00310 WP_248054888.1 51836..52750(+) (comR) [Streptococcus iners subsp. hyiners strain 29892]
ATGAACGATAAAGGATTTGGGCAGCGCGTGCGTCAGTTGCGAGAAACTGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTACGCCAATTAACCCGTATCGAAGCAGGCACTTCCAAGCCAACTTTGTCAAAGATTCAATATA
TTGCAAATCGCTTAGGTATGAGTCTTTATGAACTTATGCCTGACTATGTGAAACTCCCAAATAGGTATTTGAAGCTTAAG
TTTGAAGTTCTTCGCACACCGACTTATGAAAATGAAGAATTGATGGATAAGCGCAATCAATTGATGGAAGAAATTTATGA
TAATTATTACGATGACTTGCCAGAGGAAGAACAAGTGGCTATTGATGCATTTCAGTCTTTTGTTGATATTTATGAAACAA
AATCAGTTCATTTTGGCAAAGAGATCTTAGATGATTATTTTGAACAGGTTCATCGTAAGGATAAGTTCACAGTCAATGAT
TTATTGATTATTCGGTTGTACTTAGAACACTTGCAGGATGAGGATGTACACTCGCAAAGTTTTCAACACTTTTTAGATAT
TACCCGACATTTTCCAACACAGATGGAGGTTATCGATTCAAATGAACTTTTTATTTTGCGAGATGTAATGCTGGCCGCAA
TCGGGGTCCTTGGAAGCAAGCAGAGTTTTGACTACATTCCCCCTATTTTTGCTACTTTGGACCAGTTAATGGTTCAAACT
CATGACTTTCAGAAGAAACCTATTTTGAATCTGCTAAAGTGGAAGTATGAGCTATATGTTAATGATGACAAACAAGCCGC
TCAACAGTTGTATCAAGAAGCTGTTATGTTTGCGAAACTTATTGGGGATAATCATTTGGTGGCGAAGTTGGAGAAGGCTT
GGGTAGAAGAATACAATGGAATAGCTAAAAAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_19)

(7-68)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

61.565

96.711

0.595
  comR Streptococcus suis 05ZYH33

61.565

96.711

0.595
  comR Streptococcus suis D9

57.095

97.368

0.556
  comR Streptococcus mutans UA159

41.837

96.711

0.405
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

40.418

94.408

0.382