Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   IGS56_RS03635 Genome accession   NZ_AP022846
Coordinates   721355..722047 (+) Length   230 a.a.
NCBI ID   WP_114877327.1    Uniprot ID   -
Organism   Haemophilus influenzae strain TAMBA230     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 716355..727047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGS56_RS03615 (JPHIA_06910) ampD 717638..718189 (-) 552 WP_071162800.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  IGS56_RS03620 (JPHIA_06920) pilA 718304..718753 (+) 450 WP_103708055.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  IGS56_RS03625 (JPHIA_06930) pilB 718750..720144 (+) 1395 WP_114877323.1 GspE/PulE family protein Machinery gene
  IGS56_RS03630 (JPHIA_06940) pilC 720141..721358 (+) 1218 WP_167808414.1 type II secretion system F family protein Machinery gene
  IGS56_RS03635 (JPHIA_06950) pilD 721355..722047 (+) 693 WP_114877327.1 prepilin peptidase Machinery gene
  IGS56_RS03640 (JPHIA_06960) rho 722101..723363 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  IGS56_RS03645 (JPHIA_06970) metJ 723598..723915 (+) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  IGS56_RS03650 (JPHIA_06980) cueR 723929..724315 (-) 387 WP_114877329.1 Cu(I)-responsive transcriptional regulator -
  IGS56_RS03655 (JPHIA_06990) - 724392..724598 (+) 207 WP_005654130.1 heavy-metal-associated domain-containing protein -
  IGS56_RS03660 (JPHIA_07000) - 724573..726744 (+) 2172 WP_114877331.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26632.62 Da        Isoelectric Point: 8.8544

>NTDB_id=79418 IGS56_RS03635 WP_114877327.1 721355..722047(+) (pilD) [Haemophilus influenzae strain TAMBA230]
MIYFTMFLLGGILGIALWFYLSGFITRLQQEIYATYVELFPQNFLSFQPSVSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWFGLTLLILWAISYLDWHYQLISTTLCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=79418 IGS56_RS03635 WP_114877327.1 721355..722047(+) (pilD) [Haemophilus influenzae strain TAMBA230]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACTTTCTGTCATTTCAGCCTAGCGTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGTTCGGACTCACACTTCTTATCCTTTGGGCAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACTACACTCTGTTTATGGCTACTTACAATCGGTTTATTTGGGGCAGACAATAATTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATAATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

92.174

100

0.922
  pilD Haemophilus influenzae Rd KW20

91.739

100

0.917

Multiple sequence alignment