Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PWF74_RS01430 Genome accession   NZ_CP118627
Coordinates   278902..279597 (+) Length   231 a.a.
NCBI ID   WP_004259096.1    Uniprot ID   -
Organism   Lactococcus garvieae strain Pa-2     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 273902..284597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWF74_RS01405 (PWF74_01405) - 274135..274836 (+) 702 WP_004259114.1 DeoR/GlpR family DNA-binding transcription regulator -
  PWF74_RS01410 (PWF74_01410) pfkB 274833..275759 (+) 927 WP_165705969.1 1-phosphofructokinase -
  PWF74_RS01415 (PWF74_01415) - 275774..277678 (+) 1905 WP_014024348.1 PTS fructose transporter subunit IIABC -
  PWF74_RS01420 (PWF74_01420) - 277790..278032 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  PWF74_RS01425 (PWF74_01425) - 278249..278800 (+) 552 WP_165705968.1 YceD family protein -
  PWF74_RS01430 (PWF74_01430) covR 278902..279597 (+) 696 WP_004259096.1 response regulator transcription factor Regulator
  PWF74_RS01435 (PWF74_01435) covS 279686..281176 (+) 1491 WP_014024351.1 HAMP domain-containing histidine kinase Regulator
  PWF74_RS01440 (PWF74_01440) - 281573..283144 (+) 1572 WP_165705967.1 ABC transporter permease subunit -
  PWF74_RS01445 (PWF74_01445) - 283145..283882 (+) 738 WP_141921008.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26979.74 Da        Isoelectric Point: 5.4730

>NTDB_id=794042 PWF74_RS01430 WP_004259096.1 278902..279597(+) (covR) [Lactococcus garvieae strain Pa-2]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQGNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=794042 PWF74_RS01430 WP_004259096.1 278902..279597(+) (covR) [Lactococcus garvieae strain Pa-2]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATACCAAACTGCGGTTCAAGGCAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TTGACTTAATGCTCCCAGAGCTTGATGGCTTTGAGGTTGCACGACGCTTACGCCGTGAGAAAGATACACATATTATTATG
ATGACTGCACGTGATTCGACAATGGACCGTGTAGCAGGTCTTGATATTGGCGCAGATGACTATATTACAAAACCATTTGC
TATTGAAGAATTGTTAGCGCGTGTCCGCTCACTCTTCCGTCGTGAAGATCATATCCACACGATTGAAAAGTCCGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAGACCAACCGTACTGTACACCGTGGAAAAAAAGTTATTGACCTTACACGTCGT
GAGTACGATTTGCTTTTGACACTGATGCAAAATGTAGGTGATGTCGTAACACGTGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTGGACGTTTATATCCGTTATCTGCGTAACAAAATTGACGTGGAGGGCCGTG
AAAGCTACATCCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

87.773

99.134

0.87
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424