Detailed information NTG0791606

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: Q7621_RS01220
• Genome accession: NZ_CP131712
• Coordinates: 218085..219083 (+)
• Length: 332 a.a.
• NCBI ID: WP_001809468.1
• Uniprot ID: Q8CWU7
• Organism: Streptococcus pneumoniae strain 2008C09-280
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 213085..224083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7621_RS01200 (Q7621_01200)	-	215211..216053 (+)	843	WP_001081167.1	hypothetical protein	-
Q7621_RS01205 (Q7621_01205)	-	216109..216804 (+)	696	WP_001144904.1	GNAT family protein	-
Q7621_RS01210 (Q7621_01210)	-	216816..217232 (+)	417	WP_000628384.1	GNAT family N-acetyltransferase	-
Q7621_RS01215 (Q7621_01215)	-	217859..217951 (-)	93	WP_000970381.1	type I toxin-antitoxin system Fst family toxin	-
Q7621_RS01220 (Q7621_01220)	ruvB	218085..219083 (+)	999	WP_001809468.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
Q7621_RS01225 (Q7621_01225)	-	219064..219636 (+)	573	Protein_237	nucleotidyltransferase family protein	-
Q7621_RS01230 (Q7621_01230)	-	219867..220625 (+)	759	WP_000466719.1	isoprenyl transferase	-
Q7621_RS01235 (Q7621_01235)	-	220634..221437 (+)	804	WP_341966617.1	phosphatidate cytidylyltransferase	-
Q7621_RS01240 (Q7621_01240)	eeP	221459..222718 (+)	1260	WP_341966618.1	RIP metalloprotease RseP	Regulator

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37288.73 Da
• Isoelectric Point: 4.5053

>NTDB_id=791606 Q7621_RS01220 WP_001809468.1 218085..219083(+) (ruvB) [Streptococcus pneumoniae strain 2008C09-280]
MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPVIEKAGDLVAILNELEPGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRVRDFAQIMGNGVID
DIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAK
AYEHLGYEYSEK

Nucleotide

• Length: 999 bp

>NTDB_id=791606 Q7621_RS01220 WP_001809468.1 218085..219083(+) (ruvB) [Streptococcus pneumoniae strain 2008C09-280]
ATGAGTAGAATTTTAGATAATGAGATAATGGGGGATGAGGAGTTAGTAGAACGCACGCTCCGTCCTCAGTATTTACGTGA
ATATATTGGGCAGGATAAGGTTAAGGACCAGCTTCAAATCTTTATAGAAGCTGCCAAAATGCGAGATGAAGCGCTGGATC
ATGTCCTCTTATTTGGGCCTCCAGGTTTGGGGAAAACAACCATGGCTTTTGTCATTGCCAATGAACTGGGAGTCAATCTC
AAGCAAACGTCTGGTCCTGTTATCGAAAAAGCGGGTGATTTGGTAGCGATTTTGAATGAGTTAGAGCCTGGAGATGTCCT
CTTTATTGACGAGATTCATCGCTTACCCATGTCAGTGGAAGAAGTGCTTTATAGTGCCATGGAGGACTTCTACATCGATA
TTATGATTGGGGCTGGTGAAGGCAGTCGCAGTGTTCATTTGGAGTTGCCTCCTTTTACCTTGATTGGTGCGACGACTCGG
GCTGGTATGCTCTCAAATCCACTACGGGCACGTTTTGGGATTACAGGTCATATGGAGTATTATGCCCATGCTGACTTGAC
AGAAATTGTCGAGCGGACGGCAGATATTTTTGAGATGGAAATCACTCATGAGGCAGCATCTGAGTTGGCCCTACGTAGTC
GTGGAACCCCTCGTATTGCCAATCGTCTCCTCAAGCGCGTGCGCGATTTTGCCCAGATAATGGGGAATGGGGTAATCGAT
GATATTATTACCGATAAGGCTTTGACTATGCTGGATGTTGACCATGAAGGTTTGGACTATGTGGATCAAAAAATCCTTCG
TACCATGATTGAGATGTACAGTGGAGGACCTGTTGGTCTAGGAACTCTTTCTGTCAATATCGCCGAAGAGCGTGAGACAG
TTGAAGACATGTATGAGCCTTACTTGATTCAAAAAGGTTTTATCATGCGGACACGGTCTGGACGGGTGGCGACTGCTAAG
GCATATGAGCACTTAGGTTATGAATACAGTGAAAAATAA

Domains

Predicted by InterProScan.

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: Q8CWU7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	100	100	1
ruvB	Streptococcus pneumoniae D39	100	100	1
ruvB	Streptococcus pneumoniae TIGR4	99.096	100	0.991
ruvB	Bacillus subtilis subsp. subtilis str. 168	60.429	98.193	0.593
ruvB	Helicobacter pylori 26695	50.774	97.289	0.494
ruvB	Synechocystis sp. PCC 6803	49.84	94.277	0.47