Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   PUW52_RS01095 Genome accession   NZ_CP118078
Coordinates   194904..195197 (+) Length   97 a.a.
NCBI ID   WP_024053127.1    Uniprot ID   A0A412PLL4
Organism   Streptococcus anginosus strain VSI16     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 189904..200197
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW52_RS01060 (PUW52_01060) - 189959..190318 (+) 360 WP_003070793.1 MerR family transcriptional regulator -
  PUW52_RS01065 (PUW52_01065) glnA 190356..191702 (+) 1347 WP_024053132.1 type I glutamate--ammonia ligase -
  PUW52_RS01070 (PUW52_01070) - 191890..192255 (+) 366 WP_024053131.1 DUF1033 family protein -
  PUW52_RS01075 (PUW52_01075) comYA 192325..193266 (+) 942 WP_024053130.1 competence type IV pilus ATPase ComGA Machinery gene
  PUW52_RS01080 (PUW52_01080) comYB 193208..194230 (+) 1023 WP_024053129.1 competence type IV pilus assembly protein ComGB Machinery gene
  PUW52_RS01085 (PUW52_01085) comYC 194227..194544 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  PUW52_RS01090 (PUW52_01090) comYD 194534..194932 (+) 399 WP_022525973.1 competence type IV pilus minor pilin ComGD Machinery gene
  PUW52_RS01095 (PUW52_01095) comGE/cglE 194904..195197 (+) 294 WP_024053127.1 competence type IV pilus minor pilin ComGE Machinery gene
  PUW52_RS01100 (PUW52_01100) comGF/cglF 195181..195618 (+) 438 WP_024053126.1 competence type IV pilus minor pilin ComGF Machinery gene
  PUW52_RS01105 (PUW52_01105) comGG 195599..195925 (+) 327 WP_022525970.1 competence type IV pilus minor pilin ComGG -
  PUW52_RS01110 (PUW52_01110) comYH 195997..196950 (+) 954 WP_024053125.1 class I SAM-dependent methyltransferase Machinery gene
  PUW52_RS01115 (PUW52_01115) - 196997..198196 (+) 1200 WP_024053124.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10836.84 Da        Isoelectric Point: 10.6170

>NTDB_id=789818 PUW52_RS01095 WP_024053127.1 194904..195197(+) (comGE/cglE) [Streptococcus anginosus strain VSI16]
MGNLRKQHVKGTILLEALLALAVFVTIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIKVRVETSQQ
GIQIYHGKELILGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=789818 PUW52_RS01095 WP_024053127.1 194904..195197(+) (comGE/cglE) [Streptococcus anginosus strain VSI16]
ATGGGAAATTTAAGAAAACAACACGTTAAAGGAACGATTTTATTAGAGGCGCTGCTGGCTTTGGCTGTTTTTGTGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAGACAAAGCAAAGCCATTTGACAATGAACGGTATTAAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAAATTTATCATGGGAAGGAGCTGATTCTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PLL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

50.526

97.938

0.495
  comGE/cglE Streptococcus pneumoniae D39

50.526

97.938

0.495
  comGE/cglE Streptococcus pneumoniae R6

50.526

97.938

0.495
  comGE/cglE Streptococcus pneumoniae TIGR4

50.526

97.938

0.495
  comGE/cglE Streptococcus mitis NCTC 12261

49.474

97.938

0.485
  comGE/cglE Streptococcus mitis SK321

49.474

97.938

0.485
  comYE Streptococcus mutans UA140

45.455

100

0.464
  comYE Streptococcus mutans UA159

45.455

100

0.464