Detailed information NTG0789820

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: PUW52_RS01110
• Genome accession: NZ_CP118078
• Coordinates: 195997..196950 (+)
• Length: 317 a.a.
• NCBI ID: WP_024053125.1
• Uniprot ID: A0A412PLM5
• Organism: Streptococcus anginosus strain VSI16
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 190997..201950

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW52_RS01070 (PUW52_01070)	-	191890..192255 (+)	366	WP_024053131.1	DUF1033 family protein	-
PUW52_RS01075 (PUW52_01075)	comYA	192325..193266 (+)	942	WP_024053130.1	competence type IV pilus ATPase ComGA	Machinery gene
PUW52_RS01080 (PUW52_01080)	comYB	193208..194230 (+)	1023	WP_024053129.1	competence type IV pilus assembly protein ComGB	Machinery gene
PUW52_RS01085 (PUW52_01085)	comYC	194227..194544 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
PUW52_RS01090 (PUW52_01090)	comYD	194534..194932 (+)	399	WP_022525973.1	competence type IV pilus minor pilin ComGD	Machinery gene
PUW52_RS01095 (PUW52_01095)	comGE/cglE	194904..195197 (+)	294	WP_024053127.1	competence type IV pilus minor pilin ComGE	Machinery gene
PUW52_RS01100 (PUW52_01100)	comGF/cglF	195181..195618 (+)	438	WP_024053126.1	competence type IV pilus minor pilin ComGF	Machinery gene
PUW52_RS01105 (PUW52_01105)	comGG	195599..195925 (+)	327	WP_022525970.1	competence type IV pilus minor pilin ComGG	-
PUW52_RS01110 (PUW52_01110)	comYH	195997..196950 (+)	954	WP_024053125.1	class I SAM-dependent methyltransferase	Machinery gene
PUW52_RS01115 (PUW52_01115)	-	196997..198196 (+)	1200	WP_024053124.1	acetate kinase	-
PUW52_RS01120 (PUW52_01120)	glmS	198591..200405 (+)	1815	WP_024053123.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35821.57 Da
• Isoelectric Point: 4.2900

>NTDB_id=789820 PUW52_RS01110 WP_024053125.1 195997..196950(+) (comYH) [Streptococcus anginosus strain VSI16]
MNFEKIEQAYTLLLENVQEIQNDLLTSFYDALIEQNGSYLDGDIELDSVRQNNEKLKALKLSKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFILTFLIDQLSKKEHIDILEIGSGMGNLAETILNNTQKNVDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDSIAARYEVASTQDHTYAHHLLMEQSLKYLKSGGYAIFLAPNDLLTSSQ
SDLLKKWLQKHAQIVAMIALPESLFGNAAYAKTIFVLKKQDEQAVQPFVYALSDLQNQADLLTFSEKFQNWSQESEI

Nucleotide

• Length: 954 bp

>NTDB_id=789820 PUW52_RS01110 WP_024053125.1 195997..196950(+) (comYH) [Streptococcus anginosus strain VSI16]
ATGAATTTTGAAAAAATTGAACAGGCCTATACGCTCTTGTTAGAAAATGTCCAAGAAATCCAAAATGATCTTTTAACGAG
CTTTTATGATGCTTTGATAGAGCAAAATGGCAGCTATCTGGACGGGGATATTGAACTAGATAGTGTTCGGCAGAACAATG
AAAAACTGAAAGCGTTGAAATTAAGTAAAGAGGAATGGCGCCGAGCCTACCAATTTTTGCTGATGAAAGCAGCTCAAACA
GAGCCTTTGCAAGCCAATCATCAATTTACTCCAGATTCTATCGGGTTTATCTTAACTTTTCTCATTGACCAATTGAGTAA
AAAAGAACACATTGATATTTTGGAAATTGGTAGCGGAATGGGGAATTTAGCTGAGACGATTCTCAATAATACACAAAAAA
ATGTGGATTATCTAGGGCTGGAATTGGACGATCTGTTAATTGATATATCAGCCAGTATCGCAGATGTGATGGACGCAAAA
GTTAGTTTTGTGCAAGGTGACGCAGTACGTCCGCAAGTATTGAAAGAAAGCGATGTGATTATTAGCGATTTACCAGTTGG
CTTTTATCCTGATGATAGCATTGCGGCGCGCTATGAAGTGGCTAGTACACAGGATCATACCTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCAGGCGGTTATGCTATTTTCCTTGCACCAAATGATTTATTGACTAGTTCGCAA
AGTGATTTATTGAAGAAATGGCTACAAAAGCATGCACAAATAGTTGCAATGATTGCGTTACCAGAGTCTCTTTTTGGAAA
TGCAGCATACGCTAAAACAATTTTTGTACTGAAAAAGCAAGATGAACAAGCTGTCCAACCATTTGTTTATGCTTTATCTG
ATTTGCAGAATCAAGCGGATTTATTGACATTTAGCGAAAAGTTTCAAAATTGGAGCCAAGAAAGTGAAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-294)

3D structure

• AlphaFold DB: A0A412PLM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	61.905	99.369	0.615
comYH	Streptococcus mutans UA159	61.587	99.369	0.612