Detailed information NTG0789374

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: PUW57_RS04640
• Genome accession: NZ_CP118043
• Coordinates: 846835..849078 (+)
• Length: 747 a.a.
• NCBI ID: WP_274999121.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain VSI63
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 841835..854078

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW57_RS04615 (PUW57_04615)	-	842429..844015 (+)	1587	WP_000673089.1	DEAD/DEAH box helicase	-
PUW57_RS04620 (PUW57_04620)	-	844200..844466 (-)	267	WP_000598736.1	GIY-YIG nuclease family protein	-
PUW57_RS04625 (PUW57_04625)	-	844459..845223 (-)	765	WP_000567425.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
PUW57_RS04630 (PUW57_04630)	-	845358..846098 (+)	741	WP_000500220.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
PUW57_RS04635 (PUW57_04635)	-	846198..846851 (+)	654	WP_000461744.1	helix-hairpin-helix domain-containing protein	-
PUW57_RS04640 (PUW57_04640)	comEC/celB	846835..849078 (+)	2244	WP_274999121.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PUW57_RS04645 (PUW57_04645)	-	849204..850013 (+)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
PUW57_RS04650 (PUW57_04650)	-	850024..850968 (+)	945	WP_000200830.1	LacI family DNA-binding transcriptional regulator	-
PUW57_RS04655 (PUW57_04655)	-	851027..852019 (-)	993	WP_000800998.1	alpha/beta hydrolase	-
PUW57_RS04660 (PUW57_04660)	-	852195..852923 (+)	729	WP_000468966.1	methyltransferase domain-containing protein	-
PUW57_RS04665 (PUW57_04665)	holA	852977..854014 (+)	1038	WP_000560292.1	DNA polymerase III subunit delta	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85740.69 Da
• Isoelectric Point: 9.8332

>NTDB_id=789374 PUW57_RS04640 WP_274999121.1 846835..849078(+) (comEC/celB) [Streptococcus agalactiae strain VSI63]
MLQLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFSFIFLIYQYDRETIFKTIAIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIKVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLFQHRSFFALMSKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPIVKLSCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHYHSKCFRYCSLLIIFTLFFI
TKNPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAKRTLIPYLKSRGISKIDDLVITHTD
TDHMGDMEVISKHFKVARLITSSGSLTNSQYVKHLSKIGVAVKSIEAGDKLAVMGSYLQVLYPWHKGDGKNNDSIVLYGH
LLGKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKI
KSKIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2244 bp

>NTDB_id=789374 PUW57_RS04640 WP_274999121.1 846835..849078(+) (comEC/celB) [Streptococcus agalactiae strain VSI63]
ATGTTACAATTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTTCTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAGCAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTAAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTACACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATAATTGCAGATATCAAACTTGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATTTCAACATAGGTCTTTCTT
TGCTCTTATGTCTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCCCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCGCCTATCGTTAAATTAAGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTGTTATTAAAATGGAC
TGGGCAACTGTTTCCAAGGCCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATC
ACTAAGAATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAGGGAGATAGTATTTTAGTGAGGGATTGGTTAGG
AAAAACAATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAATCAGTCTA
ATGCTAAGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATGATTTAGTGATAACTCATACCGAT
ACAGATCATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAAC
GAATTCGCAGTACGTTAAGCATTTATCAAAGATAGGTGTAGCGGTAAAATCTATAGAAGCCGGTGATAAACTTGCTGTCA
TGGGAAGTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACAT
TTATTAGGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTT
ATCAGTAGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTA
GTGTGGTTCTAGTTTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATT
AAAAGCAAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCG
TTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-177)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-578)

• Competence protein (Competence) (215-456)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.336	100	0.486
comEC/celB	Streptococcus mitis SK321	48.465	100	0.486
comEC/celB	Streptococcus pneumoniae TIGR4	46.996	100	0.471
comEC/celB	Streptococcus pneumoniae D39	46.729	100	0.469
comEC/celB	Streptococcus pneumoniae Rx1	46.729	100	0.469
comEC/celB	Streptococcus pneumoniae R6	46.729	100	0.469
comEC	Lactococcus lactis subsp. cremoris KW2	43.087	99.732	0.43