Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   MGCS35823_RS02190 Genome accession   NZ_CP117289
Coordinates   404043..404729 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 399043..409729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS35823_RS02165 (MGCS35823_00878) ktrB 399149..400525 (-) 1377 WP_012766594.1 potassium uptake transporter channel subunit KtrB -
  MGCS35823_RS02170 (MGCS35823_00880) rsmG 400609..401322 (-) 714 WP_003058986.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  MGCS35823_RS02175 (MGCS35823_00882) - 401475..402032 (+) 558 WP_003058947.1 LemA family protein -
  MGCS35823_RS02180 (MGCS35823_00884) htpX 402079..402972 (+) 894 WP_003059035.1 zinc metalloprotease HtpX -
  MGCS35823_RS02185 (MGCS35823_00886) - 403239..403772 (+) 534 WP_014612038.1 DUF177 domain-containing protein -
  MGCS35823_RS02190 (MGCS35823_00888) covR 404043..404729 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  MGCS35823_RS02195 (MGCS35823_00890) - 404735..406234 (+) 1500 WP_003058944.1 HAMP domain-containing histidine kinase -
  MGCS35823_RS02200 (MGCS35823_00892) nrdR 406440..406934 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  MGCS35823_RS02205 (MGCS35823_00894) - 406918..408096 (+) 1179 WP_015016698.1 DnaD domain protein -
  MGCS35823_RS02210 (MGCS35823_00896) dnaI 408097..408999 (+) 903 WP_003058998.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=783433 MGCS35823_RS02190 WP_003049736.1 404043..404729(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=783433 MGCS35823_RS02190 WP_003049736.1 404043..404729(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425