NTDB

Overview

Name	vicR	Type	Regulator
Locus tag	PQ615_RS04060	Genome accession	NZ_CP117058
Coordinates	840530..841255 (+)	Length	241 a.a.
NCBI ID	WP_003101290.1	Uniprot ID	A0A3L8GIX6
Organism	Streptococcus iniae strain LSSM211007SI
Function	repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 835530..846255

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PQ615_RS04030 (PQ615_04025)	-	835637..837013 (+)	1377	WP_003101303.1	PTS sugar transporter subunit IIC	-
PQ615_RS04035 (PQ615_04030)	-	837300..837926 (+)	627	WP_003101299.1	NAD(P)-dependent oxidoreductase	-
PQ615_RS04040 (PQ615_04035)	-	837998..838813 (-)	816	WP_003101297.1	TIGR03943 family protein	-
PQ615_RS04045 (PQ615_04040)	-	838810..839715 (-)	906	WP_003101296.1	permease	-
PQ615_RS04050 (PQ615_04045)	-	839715..839858 (-)	144	WP_003101294.1	SPJ_0845 family protein	-
PQ615_RS04055 (PQ615_04050)	-	840051..840434 (+)	384	WP_003101292.1	VOC family protein	-
PQ615_RS04060 (PQ615_04055)	vicR	840530..841255 (+)	726	WP_003101290.1	response regulator transcription factor	Regulator
PQ615_RS04065 (PQ615_04060)	pnpS	841239..842567 (+)	1329	WP_003101288.1	two-component system histidine kinase PnpS	-
PQ615_RS04070 (PQ615_04065)	-	842721..843596 (+)	876	WP_003101287.1	substrate-binding domain-containing protein	-
PQ615_RS04075 (PQ615_04070)	pstC	843659..844522 (+)	864	WP_003101285.1	phosphate ABC transporter permease subunit PstC	-
PQ615_RS04080 (PQ615_04075)	pstA	844515..845330 (+)	816	WP_003101283.1	phosphate ABC transporter permease PstA	-
PQ615_RS04085 (PQ615_04080)	-	845333..845944 (+)	612	WP_016356076.1	phosphate ABC transporter ATP-binding protein	-

Sequence

Protein

Download Length: 241 a.a. Molecular weight: 28088.34 Da Isoelectric Point: 5.1365

                                >NTDB_id=782442 PQ615_RS04060 WP_003101290.1 840530..841255(+) (vicR) [Streptococcus iniae strain LSSM211007SI]

MKKTVLLVDDEEHILRLLDYHLSKEGFSIDTATDGRSALKLAETESYDFILLDIMLPQLDGIEVCKRIRAKNSKTPIMMV

SAKGEEFDKVLALELGADDYMTKPFSPRELLARVKAILRRTGKDDSQQEEFGFADQRFLVNDLVIYPERNEVYKEQDLIS

LTPKEYELLMYLVKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDDPKNPEMIKTIRGYGYQFKEMKDATK

S

Nucleotide

Download Length: 726 bp

                                >NTDB_id=782442 PQ615_RS04060 WP_003101290.1 840530..841255(+) (vicR) [Streptococcus iniae strain LSSM211007SI]

ATGAAAAAGACAGTTTTATTAGTAGACGACGAAGAGCACATCTTACGTTTATTAGACTATCATCTCAGCAAGGAAGGCTT

TAGTATTGACACAGCAACAGATGGCAGATCAGCACTAAAATTAGCTGAAACAGAAAGTTATGACTTCATTTTGTTAGACA

TCATGTTGCCCCAATTGGACGGTATTGAGGTCTGTAAACGTATCAGAGCTAAAAATAGTAAGACCCCTATTATGATGGTA

TCAGCTAAAGGGGAAGAATTTGACAAGGTCCTAGCCTTAGAACTAGGAGCTGATGATTACATGACAAAACCCTTTAGTCC

AAGGGAATTGCTGGCGCGTGTAAAAGCTATTTTAAGACGAACAGGAAAAGACGACAGCCAACAAGAAGAGTTTGGCTTCG

CTGACCAGCGATTCTTGGTCAATGACTTGGTCATTTACCCTGAAAGAAATGAAGTTTACAAAGAGCAAGACTTGATTTCC

TTAACCCCAAAAGAGTATGAACTGTTAATGTATTTAGTCAAACATCCCAATATGACCTTAACAAGAGAACGACTTTTAGA

ACGGATTTGGGGGTATGACTTTGGCCAAGAAACACGTTTAGTAGATGTTCATATTGGAAAATTAAGAGACAAAATTGAAG

ATGATCCTAAAAATCCAGAGATGATTAAAACAATCAGGGGCTATGGCTATCAGTTTAAGGAGATGAAGGATGCTACAAAA

TCTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A3L8GIX6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
vicR	Streptococcus mutans UA159	51.293	96.266	0.494
micA	Streptococcus pneumoniae Cp1015	48.918	95.851	0.469
covR	Lactococcus lactis subsp. lactis strain DGCC12653	42.194	98.34	0.415
covR	Streptococcus salivarius strain HSISS4	39.316	97.095	0.382

Detailed information NTG0782442