Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PQ615_RS03060 Genome accession   NZ_CP117058
Coordinates   649320..650006 (+) Length   228 a.a.
NCBI ID   WP_003101668.1    Uniprot ID   -
Organism   Streptococcus iniae strain LSSM211007SI     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 644320..655006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQ615_RS03035 (PQ615_03030) ktrB 644564..645925 (-) 1362 WP_017794720.1 potassium uptake transporter channel subunit KtrB -
  PQ615_RS03040 (PQ615_03035) rsmG 646017..646733 (-) 717 WP_003101672.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  PQ615_RS03045 (PQ615_03040) - 646878..647435 (+) 558 WP_003101671.1 LemA family protein -
  PQ615_RS03050 (PQ615_03045) htpX 647474..648370 (+) 897 WP_003101670.1 zinc metalloprotease HtpX -
  PQ615_RS03055 (PQ615_03050) - 648558..649091 (+) 534 WP_003101669.1 DUF177 domain-containing protein -
  PQ615_RS03060 (PQ615_03055) covR 649320..650006 (+) 687 WP_003101668.1 two-component system response regulator CovR Regulator
  PQ615_RS03065 (PQ615_03060) - 650009..651496 (+) 1488 WP_037584827.1 HAMP domain-containing histidine kinase -
  PQ615_RS03070 (PQ615_03065) nrdR 651642..652136 (+) 495 WP_003101666.1 transcriptional regulator NrdR -
  PQ615_RS03075 (PQ615_03070) - 652120..653307 (+) 1188 WP_003101665.1 DnaD domain protein -
  PQ615_RS03080 (PQ615_03075) dnaI 653308..654210 (+) 903 WP_003101664.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26670.62 Da        Isoelectric Point: 4.6541

>NTDB_id=782435 PQ615_RS03060 WP_003101668.1 649320..650006(+) (covR) [Streptococcus iniae strain LSSM211007SI]
MTKKILIVEDEKNLARFVSLELQHEGYEVTVEVNGREGLDTALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKSPNQGIYRDLVLNPQNRSVNRGDEEISLTKREY
DLLNILMSNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDMQGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=782435 PQ615_RS03060 WP_003101668.1 649320..650006(+) (covR) [Streptococcus iniae strain LSSM211007SI]
ATGACAAAAAAAATTCTAATTGTTGAAGATGAAAAAAATCTTGCAAGGTTTGTTTCATTAGAATTGCAACACGAAGGTTA
CGAAGTAACTGTAGAAGTGAATGGTCGTGAAGGACTTGACACAGCGCTTGAAAAAGATTTTGATTTAATCTTGCTTGATT
TGATGTTACCTGAAATGGATGGTTTTGAAGTGACCCGTCGTCTTCAAACTGAAAAAACAACCTACATTATGATGATGACA
GCACGCGATTCTATCATGGACGTGGTTGCTGGTTTGGATCGTGGTGCAGATGATTATATTGTTAAGCCATTTGCTATTGA
AGAATTATTGGCACGTATTCGTGCAATTTTCCGTCGTCAAGATATTGAAACTGAGAAAAAATCTCCTAATCAAGGTATTT
ACCGTGATTTAGTCTTAAATCCACAAAACCGTTCTGTAAACCGTGGAGATGAAGAAATTTCATTGACAAAACGCGAATAT
GATTTGTTAAACATTTTAATGAGCAATATGAATCGTGTCATGACGCGTGAAGAGTTGCTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAACGTTGTTGACGTGTATATTCGTTACCTACGTGGAAAAATCGATATGCAAGGACGTGAGTCCT
ATATTCAAACTGTTCGTGGAATGGGATATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.52

99.561

0.662
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.434