Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NL414_RS02745 Genome accession   NZ_CP117013
Coordinates   483098..484222 (+) Length   374 a.a.
NCBI ID   WP_000228562.1    Uniprot ID   -
Organism   Escherichia coli strain MLI114     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 478098..489222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL414_RS02720 (NL414_002720) mscL 478224..478634 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  NL414_RS02725 (NL414_002725) trkA 478764..480140 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  NL414_RS02730 (NL414_002730) rsmB 480162..481451 (-) 1290 WP_001469469.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  NL414_RS02735 (NL414_002735) fmt 481497..482444 (-) 948 WP_000004443.1 methionyl-tRNA formyltransferase -
  NL414_RS02740 (NL414_002740) def 482459..482968 (-) 510 WP_000114984.1 peptide deformylase -
  NL414_RS02745 (NL414_002745) dprA 483098..484222 (+) 1125 WP_000228562.1 DNA-protecting protein DprA Machinery gene
  NL414_RS02750 (NL414_002750) smg 484194..484667 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  NL414_RS02755 (NL414_002755) yrdD 484696..485238 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  NL414_RS02760 (NL414_002760) tsaC 485243..485815 (+) 573 WP_001366671.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  NL414_RS02765 (NL414_002765) aroE 485820..486638 (+) 819 WP_000451231.1 shikimate dehydrogenase -
  NL414_RS02770 (NL414_002770) yrdB 486635..486892 (+) 258 WP_001070567.1 DUF1488 domain-containing protein -
  NL414_RS02775 (NL414_002775) yrdA 486868..487422 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40975.98 Da        Isoelectric Point: 6.4377

>NTDB_id=781990 NL414_RS02745 WP_000228562.1 483098..484222(+) (dprA) [Escherichia coli strain MLI114]
MVDTEIWLRLMSISSLYGDNMVRIAHWLAKQSYIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVAGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=781990 NL414_RS02745 WP_000228562.1 483098..484222(+) (dprA) [Escherichia coli strain MLI114]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATAATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGTATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGCAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTTTAAGTAAAGGTGTACTAGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGACCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

48.71

82.888

0.404
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

43.917

90.107

0.396
  dprA Legionella pneumophila strain ERS1305867

44.377

87.968

0.39