Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   PHA78_RS09220 Genome accession   NZ_CP116604
Coordinates   1898996..1899640 (+) Length   214 a.a.
NCBI ID   WP_272158069.1    Uniprot ID   -
Organism   Streptococcus sp. HN38     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1893996..1904640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS09195 - 1894657..1895994 (-) 1338 WP_024375864.1 hemolysin family protein -
  PHA78_RS09200 - 1896127..1896906 (+) 780 WP_272158064.1 ABC transporter ATP-binding protein -
  PHA78_RS09205 - 1896922..1897476 (-) 555 WP_024378109.1 class I SAM-dependent methyltransferase -
  PHA78_RS09210 - 1897486..1898004 (-) 519 WP_024378110.1 TetR/AcrR family transcriptional regulator -
  PHA78_RS09215 - 1898126..1898944 (+) 819 WP_272158067.1 cation diffusion facilitator family transporter -
  PHA78_RS09220 cclA/cilC 1898996..1899640 (+) 645 WP_272158069.1 A24 family peptidase Machinery gene
  PHA78_RS09225 - 1899748..1901208 (+) 1461 WP_099806785.1 nicotinate phosphoribosyltransferase -
  PHA78_RS09230 nadE 1901221..1902045 (+) 825 WP_024378114.1 ammonia-dependent NAD(+) synthetase -
  PHA78_RS09235 trpB 1902087..1903262 (-) 1176 WP_272158071.1 tryptophan synthase subunit beta -
  PHA78_RS09240 - 1903797..1904318 (-) 522 WP_044767267.1 VanZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24402.46 Da        Isoelectric Point: 8.7013

>NTDB_id=778779 PHA78_RS09220 WP_272158069.1 1898996..1899640(+) (cclA/cilC) [Streptococcus sp. HN38]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPSSHCNACKRRLKAWDLIPILSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LLVLLCHFQVLNLTETILILAGLVLTIYDIKHQEYPFAVWLIFTFIALVLSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLSLLFGFTEILWIIQLSSIFGLAIFFIFKPKSLPYVPFLFLASLVINITL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=778779 PHA78_RS09220 WP_272158069.1 1898996..1899640(+) (cclA/cilC) [Streptococcus sp. HN38]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCCTCTAGTCACTGCAATGCCTGCAAACGACGGCTAAAAGCTTGGGATCTCATACCAATCCTGTCCC
AACTTTCCACAAAATCTAAATGCCGTTACTGCAAGGCGAAAATTCCTTATTGGTATCTGGGACTGGAGTTCTTAGCTGGT
CTATTGGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCATCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAACATCAGGAATATCCTTTTGCTGTCTGGCTCATTTTTACTTTTATAGCTCTGGTGCTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGCGACTTTCTC
TATCTAGCAAGTCTGTCTCTTTTGTTTGGCTTTACAGAAATTCTTTGGATTATTCAGCTTAGTTCCATCTTTGGACTGGC
AATCTTTTTTATCTTTAAACCAAAATCCCTCCCTTATGTTCCTTTTCTATTTTTAGCCAGTCTAGTCATCAATATCACTC
TCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

51.185

98.598

0.505
  cclA/cilC Streptococcus pneumoniae Rx1

50.732

95.794

0.486
  cclA/cilC Streptococcus pneumoniae D39

50.732

95.794

0.486
  cclA/cilC Streptococcus pneumoniae R6

50.732

95.794

0.486
  cclA/cilC Streptococcus mitis NCTC 12261

48.341

98.598

0.477
  cclA/cilC Streptococcus pneumoniae TIGR4

49.268

95.794

0.472