Detailed information NTG0778774

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: PHA78_RS07390
• Genome accession: NZ_CP116604
• Coordinates: 1546751..1548100 (-)
• Length: 449 a.a.
• NCBI ID: WP_002935841.1
• Uniprot ID: G7SGQ2
• Organism: Streptococcus sp. HN38
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1541751..1553100

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PHA78_RS07375	pbp2b	1541862..1543934 (-)	2073	WP_272157910.1	penicillin-binding protein PBP2B	-
PHA78_RS07380	vga(F)	1544025..1545410 (-)	1386	WP_032500526.1	ABC-F type ribosomal protection protein Vga(F)	-
PHA78_RS07385	vicX	1545941..1546744 (-)	804	WP_024376691.1	MBL fold metallo-hydrolase	Regulator
PHA78_RS07390	micB	1546751..1548100 (-)	1350	WP_002935841.1	cell wall metabolism sensor histidine kinase VicK	Regulator
PHA78_RS07395	micA	1548093..1548797 (-)	705	WP_004298854.1	response regulator YycF	Regulator
PHA78_RS07400	-	1548991..1549752 (+)	762	WP_004298852.1	amino acid ABC transporter ATP-binding protein	-
PHA78_RS07405	-	1549763..1550602 (+)	840	WP_029175933.1	transporter substrate-binding domain-containing protein	-
PHA78_RS07410	-	1550617..1551315 (+)	699	WP_029185563.1	amino acid ABC transporter permease	-
PHA78_RS07415	-	1551330..1551989 (+)	660	WP_029185562.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51039.08 Da
• Isoelectric Point: 4.5202

>NTDB_id=778774 PHA78_RS07390 WP_002935841.1 1546751..1548100(-) (micB) [Streptococcus sp. HN38]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide

• Length: 1350 bp

>NTDB_id=778774 PHA78_RS07390 WP_002935841.1 1546751..1548100(-) (micB) [Streptococcus sp. HN38]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAACGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCTTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGATCGTTACACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTACATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTAACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGCATTGATAATCAGGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGTCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGATCGATTCTATCGCGTGGACAAGGCACGATCTCGTGCTCAAGGCGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGTTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• PAS fold (PAS) (96-199)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

3D structure

• AlphaFold DB: G7SGQ2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	70.183	97.105	0.682
vicK	Streptococcus mutans UA159	70.72	89.755	0.635