Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   PHA78_RS07395 Genome accession   NZ_CP116604
Coordinates   1548093..1548797 (-) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus sp. HN38     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1543093..1553797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS07380 vga(F) 1544025..1545410 (-) 1386 WP_032500526.1 ABC-F type ribosomal protection protein Vga(F) -
  PHA78_RS07385 vicX 1545941..1546744 (-) 804 WP_024376691.1 MBL fold metallo-hydrolase Regulator
  PHA78_RS07390 micB 1546751..1548100 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PHA78_RS07395 micA 1548093..1548797 (-) 705 WP_004298854.1 response regulator YycF Regulator
  PHA78_RS07400 - 1548991..1549752 (+) 762 WP_004298852.1 amino acid ABC transporter ATP-binding protein -
  PHA78_RS07405 - 1549763..1550602 (+) 840 WP_029175933.1 transporter substrate-binding domain-containing protein -
  PHA78_RS07410 - 1550617..1551315 (+) 699 WP_029185563.1 amino acid ABC transporter permease -
  PHA78_RS07415 - 1551330..1551989 (+) 660 WP_029185562.1 amino acid ABC transporter permease -
  PHA78_RS07420 - 1552112..1553155 (+) 1044 WP_272157911.1 acyltransferase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=778775 PHA78_RS07395 WP_004298854.1 1548093..1548797(-) (micA) [Streptococcus sp. HN38]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=778775 PHA78_RS07395 WP_004298854.1 1548093..1548797(-) (micA) [Streptococcus sp. HN38]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGCGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTCTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAAGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGTGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGGACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376