Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   PHA78_RS04260 Genome accession   NZ_CP116604
Coordinates   853534..854913 (+) Length   459 a.a.
NCBI ID   WP_099807063.1    Uniprot ID   -
Organism   Streptococcus sp. HN38     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 848534..859913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS04230 pstA 848856..849743 (+) 888 WP_029178759.1 phosphate ABC transporter permease PstA -
  PHA78_RS04235 pstB 849768..850571 (+) 804 WP_029187991.1 phosphate ABC transporter ATP-binding protein PstB -
  PHA78_RS04240 pstB 850583..851341 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  PHA78_RS04245 phoU 851370..852026 (+) 657 WP_002940865.1 phosphate signaling complex protein PhoU -
  PHA78_RS04250 - 852176..852724 (+) 549 WP_257213254.1 hypothetical protein -
  PHA78_RS04255 ciaR 852870..853541 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  PHA78_RS04260 ciaH 853534..854913 (+) 1380 WP_099807063.1 HAMP domain-containing sensor histidine kinase Regulator
  PHA78_RS04265 - 855099..856244 (+) 1146 WP_272158475.1 transglutaminase domain-containing protein -
  PHA78_RS04270 - 856458..857493 (+) 1036 WP_099778716.1 IS630 family transposase -
  PHA78_RS04275 rpsT 857600..857848 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  PHA78_RS04280 coaA 857907..858827 (-) 921 WP_099807285.1 type I pantothenate kinase -
  PHA78_RS04285 - 858936..859526 (+) 591 WP_029179557.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51963.67 Da        Isoelectric Point: 6.1945

>NTDB_id=778763 PHA78_RS04260 WP_099807063.1 853534..854913(+) (ciaH) [Streptococcus sp. HN38]
MPKRLKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDVDQLKLGINTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=778763 PHA78_RS04260 WP_099807063.1 853534..854913(+) (ciaH) [Streptococcus sp. HN38]
ATGCCTAAGCGATTAAAAAAATTAATGTACACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAGCCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACGTATGAGCCTAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGT
AGATCAGCTGAAATTAGGTATCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCAGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACGGTTGAATCAAGTTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTAGCCAGTATTTACCTATCGAATCTTAGCATGCGTCCAATTCTAATCAGTTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTACGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTTCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCTGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGACGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAACAAATTATCAAGACATTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50.216

100

0.508
  ciaH Streptococcus pneumoniae D39

50.216

100

0.508
  ciaH Streptococcus pneumoniae R6

50.216

100

0.508
  ciaH Streptococcus pneumoniae TIGR4

50.216

100

0.508
  ciaH Streptococcus mutans UA159

49.451

99.129

0.49