Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   PFZ59_RS06370 Genome accession   NZ_CP116393
Coordinates   1239916..1240560 (-) Length   214 a.a.
NCBI ID   WP_024396126.1    Uniprot ID   A0A0Z8EJ61
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1234916..1245560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS06355 (PFZ59_06355) trpB 1236113..1237288 (+) 1176 WP_024409516.1 tryptophan synthase subunit beta -
  PFZ59_RS06360 (PFZ59_06360) nadE 1237511..1238335 (-) 825 WP_205013296.1 ammonia-dependent NAD(+) synthetase -
  PFZ59_RS06365 (PFZ59_06365) - 1238348..1239808 (-) 1461 WP_044684097.1 nicotinate phosphoribosyltransferase -
  PFZ59_RS06370 (PFZ59_06370) cclA/cilC 1239916..1240560 (-) 645 WP_024396126.1 A24 family peptidase Machinery gene
  PFZ59_RS06375 (PFZ59_06375) - 1240614..1241432 (-) 819 WP_208582558.1 cation diffusion facilitator family transporter -
  PFZ59_RS06380 (PFZ59_06380) - 1241554..1242072 (+) 519 WP_063076880.1 TetR/AcrR family transcriptional regulator -
  PFZ59_RS06385 (PFZ59_06385) - 1242082..1242636 (+) 555 WP_002942863.1 class I SAM-dependent methyltransferase -
  PFZ59_RS06390 (PFZ59_06390) - 1242696..1243025 (+) 330 WP_277696633.1 IS630 transposase-related protein -
  PFZ59_RS06395 (PFZ59_06395) - 1243099..1243545 (+) 447 WP_277697757.1 transposase -
  PFZ59_RS06400 (PFZ59_06400) - 1243527..1244327 (-) 801 WP_277696634.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24255.27 Da        Isoelectric Point: 8.4760

>NTDB_id=777099 PFZ59_RS06370 WP_024396126.1 1239916..1240560(-) (cclA/cilC) [Streptococcus suis strain SS/UPM/MY/F001]
MKTIILFFLGASIGSFLGLVIDRFPEQSIISPSSHCNACKRRLKAWDLIPILSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LVVLLCHFQVLNLTETILSLAGLVLTIYDIKHQEYPFAVWLVFTFTALVLSQLNWLFCGFLLLAYLTEKWQFNIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFTIFKPKSIPYVPLLFLSSIPIILCI

Nucleotide


Download         Length: 645 bp        

>NTDB_id=777099 PFZ59_RS06370 WP_024396126.1 1239916..1240560(-) (cclA/cilC) [Streptococcus suis strain SS/UPM/MY/F001]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCAATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCTCCCCCTCTAGTCACTGCAATGCCTGCAAGCGACGGCTCAAGGCCTGGGACCTAATACCCATCCTGTCCC
AGCTTTCGACAAAATCTAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGATTGGAATTCTTAGCTGGT
CTAGTTGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCAGCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAACATCAGGAATATCCTTTTGCTGTCTGGCTCGTTTTTACTTTTACAGCTCTGGTACTCTCCCAGCTCA
ACTGGCTCTTCTGTGGCTTTTTACTCTTGGCCTATCTAACTGAAAAATGGCAATTCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCACTATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTTTTTCTTTCAAGTATTCCTATCATTCTGTGCA
TCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8EJ61

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.057

99.065

0.486
  cclA/cilC Streptococcus pneumoniae Rx1

48.544

96.262

0.467
  cclA/cilC Streptococcus pneumoniae D39

48.544

96.262

0.467
  cclA/cilC Streptococcus pneumoniae R6

48.544

96.262

0.467
  cclA/cilC Streptococcus pneumoniae TIGR4

47.573

96.262

0.458
  cclA/cilC Streptococcus mitis NCTC 12261

44.811

99.065

0.444