Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MWM06_RS08685 Genome accession   NZ_AP025596
Coordinates   1575885..1576532 (-) Length   215 a.a.
NCBI ID   WP_244360435.1    Uniprot ID   -
Organism   Thermus thermophilus strain SNM1-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1570885..1581532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM06_RS08655 (TthSNM11_17370) - 1571403..1572275 (+) 873 WP_011173402.1 SIS domain-containing protein -
  MWM06_RS08660 (TthSNM11_17380) - 1572279..1572959 (+) 681 WP_244340622.1 endonuclease V -
  MWM06_RS08665 (TthSNM11_17390) - 1572965..1573606 (+) 642 WP_011228617.1 lysophospholipid acyltransferase family protein -
  MWM06_RS08670 (TthSNM11_17400) - 1573741..1574016 (+) 276 WP_338139318.1 HU family DNA-binding protein -
  MWM06_RS08675 (TthSNM11_17410) - 1574041..1574883 (-) 843 WP_014510567.1 hypothetical protein -
  MWM06_RS08680 (TthSNM11_17420) - 1574890..1575888 (-) 999 WP_124104263.1 M20/M25/M40 family metallo-hydrolase -
  MWM06_RS08685 (TthSNM11_17430) vraR 1575885..1576532 (-) 648 WP_244360435.1 response regulator transcription factor Regulator
  MWM06_RS08690 (TthSNM11_17440) - 1576570..1577790 (+) 1221 WP_244360437.1 methyltransferase domain-containing protein -
  MWM06_RS08695 (TthSNM11_17450) aroQ 1577827..1578276 (+) 450 WP_011173409.1 type II 3-dehydroquinate dehydratase -
  MWM06_RS08700 (TthSNM11_17460) gyrA 1578352..1580769 (+) 2418 WP_008632827.1 DNA gyrase subunit A -
  MWM06_RS08705 (TthSNM11_17470) cutA 1580769..1581080 (+) 312 WP_008632829.1 divalent-cation tolerance protein CutA -
  MWM06_RS08710 (TthSNM11_17480) - 1581077..1581502 (+) 426 WP_011173412.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 24324.95 Da        Isoelectric Point: 5.6663

>NTDB_id=77597 MWM06_RS08685 WP_244360435.1 1575885..1576532(-) (vraR) [Thermus thermophilus strain SNM1-1]
MIRVLLADDHALFRQGLKSLLEAEGDFRVVGEAKDGWEAMRHALETKPDVILMDIQMPGLDGVQATQAILKEWPQAKVIM
LTMYRQDAYVFEAVKAGARGYLFKDVDARELVDAIRRVHAGEVLLDAELAGHIIQDFRAKKEASQPLHAELSEREVQILR
LVAQGYTNQEIAAELQLSEKTVRNRLSEIFQKLHLNNRTQAALYAIREGLARPEE

Nucleotide


Download         Length: 648 bp        

>NTDB_id=77597 MWM06_RS08685 WP_244360435.1 1575885..1576532(-) (vraR) [Thermus thermophilus strain SNM1-1]
GTGATCCGGGTTCTTCTGGCGGACGACCACGCCCTTTTCCGCCAGGGGCTGAAAAGCCTTCTGGAGGCTGAGGGGGACTT
CCGGGTGGTGGGGGAGGCCAAGGACGGATGGGAGGCCATGCGCCACGCCCTGGAGACCAAGCCCGACGTGATCCTCATGG
ACATCCAGATGCCGGGCCTGGACGGGGTGCAGGCCACCCAGGCCATCCTCAAGGAGTGGCCTCAGGCCAAGGTCATCATG
CTCACCATGTACCGCCAGGACGCCTACGTCTTTGAGGCGGTGAAGGCGGGGGCCCGGGGCTACCTCTTCAAGGACGTGGA
CGCGAGGGAGCTGGTGGACGCCATCCGCCGCGTCCACGCAGGGGAGGTGCTTCTGGACGCGGAGCTTGCCGGGCACATCA
TCCAGGACTTCCGCGCCAAGAAGGAGGCCAGCCAGCCCCTCCACGCCGAGCTTTCCGAGCGCGAGGTCCAGATCCTGAGG
CTGGTGGCCCAGGGGTACACCAACCAGGAGATCGCCGCCGAGCTTCAGCTTTCCGAGAAGACGGTGCGCAACCGCCTTTC
GGAAATTTTCCAGAAGCTTCACCTCAACAACCGGACCCAGGCGGCCCTTTACGCCATCCGGGAGGGGTTGGCGAGGCCCG
AAGAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(151-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.627

97.209

0.405
  degU Bacillus subtilis subsp. subtilis str. 168

39.189

100

0.405
  letA Legionella pneumophila str. Paris

37.5

96.744

0.363
  letA Legionella pneumophila strain ERS1305867

37.5

96.744

0.363

Multiple sequence alignment