Detailed information    

insolico Bioinformatically predicted

Overview

Name   degS   Type   Regulator
Locus tag   PF996_RS18610 Genome accession   NZ_CP116014
Coordinates   3619454..3620617 (-) Length   387 a.a.
NCBI ID   WP_007407484.1    Uniprot ID   A3KLC1
Organism   Bacillus velezensis strain SRCM124633     
Function   phosphorylation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3614454..3625617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PF996_RS18580 (PF996_18580) - 3614719..3615138 (-) 420 WP_014419009.1 TIGR03826 family flagellar region protein -
  PF996_RS18585 (PF996_18585) comFC 3615212..3615901 (-) 690 WP_217425079.1 phosphoribosyltransferase family protein Machinery gene
  PF996_RS18590 (PF996_18590) - 3615907..3616191 (-) 285 WP_017418816.1 late competence development ComFB family protein -
  PF996_RS18595 (PF996_18595) comFA 3616249..3617634 (-) 1386 WP_017418815.1 DEAD/DEAH box helicase Machinery gene
  PF996_RS18600 (PF996_18600) - 3617742..3618590 (-) 849 WP_003151387.1 DegV family protein -
  PF996_RS18605 (PF996_18605) degU 3618688..3619377 (-) 690 WP_003219701.1 two-component system response regulator DegU Regulator
  PF996_RS18610 (PF996_18610) degS 3619454..3620617 (-) 1164 WP_007407484.1 two-component sensor histidine kinase DegS Regulator
  PF996_RS18615 (PF996_18615) - 3620840..3621487 (+) 648 WP_007614107.1 YigZ family protein -
  PF996_RS18620 (PF996_18620) - 3621492..3622679 (+) 1188 WP_271265672.1 LCP family protein -
  PF996_RS18625 (PF996_18625) - 3622778..3623854 (-) 1077 WP_003151382.1 glycosyltransferase family 4 protein -
  PF996_RS18630 (PF996_18630) tuaH 3623986..3625182 (-) 1197 WP_071182023.1 teichuronic acid biosynthesis protein TuaH -

Sequence

Protein


Download         Length: 387 a.a.        Molecular weight: 45014.78 Da        Isoelectric Point: 6.8616

>NTDB_id=775295 PF996_RS18610 WP_007407484.1 3619454..3620617(-) (degS) [Bacillus velezensis strain SRCM124633]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide


Download         Length: 1164 bp        

>NTDB_id=775295 PF996_RS18610 WP_007407484.1 3619454..3620617(-) (degS) [Bacillus velezensis strain SRCM124633]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATTATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGCCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGATAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(291-384)

Sensor protein DegS (DegS)

(12-170)

Histidine kinase (HisKA_3)

(180-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degS Bacillus subtilis subsp. subtilis str. 168

95.584

99.483

0.951