Detailed information NTG0774934

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: PF975_RS02820
• Genome accession: NZ_CP116010
• Coordinates: 552652..553815 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain SRCM123815
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 547652..558815

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PF975_RS02800 (PF975_02800)	tuaH	548068..549264 (+)	1197	WP_014419014.1	teichuronic acid biosynthesis protein TuaH	-
PF975_RS02805 (PF975_02805)	-	549397..550473 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
PF975_RS02810 (PF975_02810)	-	550563..551777 (-)	1215	WP_014419013.1	LCP family protein	-
PF975_RS02815 (PF975_02815)	-	551782..552429 (-)	648	WP_007614107.1	YigZ family protein	-
PF975_RS02820 (PF975_02820)	degS	552652..553815 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
PF975_RS02825 (PF975_02825)	degU	553892..554581 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
PF975_RS02830 (PF975_02830)	-	554679..555527 (+)	849	WP_003151387.1	DegV family protein	-
PF975_RS02835 (PF975_02835)	comFA	555635..557020 (+)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
PF975_RS02840 (PF975_02840)	-	557078..557362 (+)	285	WP_014419011.1	late competence development ComFB family protein	-
PF975_RS02845 (PF975_02845)	comFC	557368..558057 (+)	690	WP_197535984.1	ComF family protein	Machinery gene
PF975_RS02850 (PF975_02850)	-	558131..558550 (+)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=774934 PF975_RS02820 WP_007407484.1 552652..553815(+) (degS) [Bacillus velezensis strain SRCM123815]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=774934 PF975_RS02820 WP_007407484.1 552652..553815(+) (degS) [Bacillus velezensis strain SRCM123815]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951