Detailed information NTG0077276

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: H7K64_RS18200
• Genome accession: NZ_AP022227
• Coordinates: 3895288..3897507 (-)
• Length: 739 a.a.
• NCBI ID: WP_182815989.1
• Uniprot ID: A0A6S5U108
• Organism: Pseudomonas putida strain WP8-W18-CRE-01
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3890288..3902507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7K64_RS18165 (WP8W18C01_36090)	murB	3890635..3891651 (-)	1017	WP_043214395.1	UDP-N-acetylmuramate dehydrogenase	-
H7K64_RS18170 (WP8W18C01_36100)	-	3891648..3892112 (-)	465	WP_043214393.1	low molecular weight protein-tyrosine-phosphatase	-
H7K64_RS18175 (WP8W18C01_36110)	kdsB	3892112..3892876 (-)	765	WP_070573253.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
H7K64_RS18180 (WP8W18C01_36120)	-	3892873..3893058 (-)	186	WP_003247142.1	Trm112 family protein	-
H7K64_RS18185 (WP8W18C01_36130)	lpxK	3893101..3894111 (-)	1011	WP_090343775.1	tetraacyldisaccharide 4'-kinase	-
H7K64_RS18190 (WP8W18C01_36140)	-	3894111..3894545 (-)	435	WP_043214387.1	ExbD/TolR family protein	-
H7K64_RS18195 (WP8W18C01_36150)	exbB	3894542..3895177 (-)	636	WP_043214385.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
H7K64_RS18200 (WP8W18C01_36160)	comA	3895288..3897507 (-)	2220	WP_182815989.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H7K64_RS18205 (WP8W18C01_36170)	-	3897650..3898291 (+)	642	WP_139205743.1	DUF2062 domain-containing protein	-
H7K64_RS18210 (WP8W18C01_36180)	-	3898175..3898954 (-)	780	WP_043214381.1	ABC transporter permease	-
H7K64_RS18215 (WP8W18C01_36190)	-	3898951..3899883 (-)	933	WP_070573244.1	ABC transporter ATP-binding protein	-
H7K64_RS18220 (WP8W18C01_36200)	-	3900024..3900647 (-)	624	WP_182815991.1	glutathione S-transferase	-

Sequence

Protein

• Length: 739 a.a.
• Molecular weight: 79888.83 Da
• Isoelectric Point: 10.6082

>NTDB_id=77276 H7K64_RS18200 WP_182815989.1 3895288..3897507(-) (comA) [Pseudomonas putida strain WP8-W18-CRE-01]
MRTGMFALALGLLSLRFLPALPSVGAMLTMLLLGVVCLPGRARAVGCFLLGMSWACWSAQNALDDRLESALDGRTLWLEG
RVVGLPALRGQSVRFELADPTSRRTALPRRLQLNWFEGPQLSAGEYWRLAVTLKRPHGLLNPHGPDWEALFLARRIGAVG
TVKAGQLLAPATNNWRDAVRQRLLAVDAQGREGALAALVLGDGSGLARSEWQALQATGTVHLMVISGQHIGLVAGLVYGL
VAWLARLGLWPQRLPWLPWACALSLVSALGYGGLAGFGVPVQRACLMLAMVLLWRLHFSHLGALLPLLAALCGVLLIEPL
ASLLPGFWLSFAAVAVLVFCFAGRLGGWRPWQAWSRAQWVVAVGLLPALLALGLPISLTAPLANLLAVPWISFAVLPLAL
LGSALLPLGQPGELLLWWAGGLLEILFQQLALLGQWRPAWEPQALTPWAGLLVGLGAALLLLPRGVPLRGLGGVMLMALW
APREPVPQGQVEVLQLDVGQGLAVLLRTRTHSLLYDAGPAKGDMDLGDRVVLPTLRKLGVKHLDLMLISHGHADHAGGAA
AIGRGLPLGRVLAGEPEQLPEALRARRCVSGERWHWDGVDFMLWQWAGGPAGNERSCALLVQAQGERLLLAGDMEAGAER
AWLAATDAPRIDWLQAPHHGSRSSSTEPFIRATSPRGVMISRGRYNSFGHPHPQVVERYRRYGLSVHDTAIEGALRLRLG
THGEVEGLRAQRRFWRQVQ

Nucleotide

• Length: 2220 bp

>NTDB_id=77276 H7K64_RS18200 WP_182815989.1 3895288..3897507(-) (comA) [Pseudomonas putida strain WP8-W18-CRE-01]
ATGCGCACAGGGATGTTCGCGCTCGCACTCGGGCTGTTGAGCCTGCGTTTTCTGCCTGCATTGCCATCGGTCGGCGCGAT
GCTGACGATGCTGTTGCTCGGCGTGGTTTGTCTTCCTGGCAGAGCCAGGGCTGTAGGTTGCTTTCTCCTCGGAATGAGCT
GGGCCTGTTGGTCGGCGCAAAACGCCTTGGATGATCGTCTGGAATCCGCGTTGGATGGGCGAACCCTGTGGCTGGAGGGG
CGGGTGGTGGGATTGCCCGCACTACGAGGGCAATCCGTGCGCTTCGAGCTTGCGGACCCTACCTCGCGTCGCACCGCCTT
GCCGCGTCGGCTTCAGTTGAACTGGTTCGAGGGGCCACAACTGAGCGCCGGCGAGTACTGGCGCCTGGCTGTCACGCTCA
AGCGACCCCATGGCCTGCTCAACCCCCATGGTCCCGACTGGGAGGCGCTTTTTCTCGCGCGGCGGATCGGCGCCGTGGGC
ACCGTCAAGGCTGGGCAGTTACTGGCACCCGCCACGAACAACTGGCGCGACGCGGTGCGCCAACGCTTGCTGGCAGTCGA
TGCCCAGGGGCGCGAAGGTGCCCTGGCGGCGCTGGTCCTGGGGGATGGCTCGGGGCTTGCGCGCTCGGAATGGCAGGCGT
TGCAGGCCACCGGTACGGTGCACTTGATGGTGATTTCCGGCCAGCACATCGGCTTGGTGGCCGGGCTGGTCTATGGCTTG
GTGGCGTGGCTGGCGCGCCTGGGCCTGTGGCCCCAGCGTCTGCCATGGTTGCCTTGGGCGTGCGCGCTGAGTCTGGTTTC
AGCGTTGGGGTACGGCGGGCTCGCAGGGTTCGGTGTGCCGGTGCAGCGAGCTTGCCTGATGCTGGCGATGGTCCTGCTCT
GGCGTCTGCACTTCAGTCATCTGGGGGCGCTCCTGCCGTTGCTGGCTGCCCTGTGTGGCGTGCTGCTGATCGAACCGTTG
GCGAGCCTGTTGCCCGGGTTTTGGCTATCGTTCGCCGCAGTCGCCGTTCTGGTGTTCTGCTTTGCCGGGCGCCTCGGCGG
CTGGCGGCCGTGGCAAGCCTGGAGCAGGGCGCAATGGGTGGTCGCGGTGGGCTTGTTGCCGGCCTTGCTGGCGCTGGGTT
TGCCGATCAGCCTGACAGCGCCGCTGGCCAATCTGTTGGCGGTACCCTGGATCAGTTTTGCCGTGTTGCCGTTGGCGCTG
CTGGGCAGTGCGCTGTTGCCGCTGGGCCAGCCCGGTGAGCTGTTGCTGTGGTGGGCAGGCGGGTTGCTGGAAATATTGTT
TCAGCAGCTGGCGCTGTTGGGGCAATGGCGTCCGGCCTGGGAGCCCCAGGCATTGACGCCGTGGGCGGGACTGCTGGTCG
GATTGGGGGCGGCGTTGCTGTTGCTGCCCCGGGGTGTGCCGCTGCGTGGACTGGGGGGCGTGATGCTGATGGCTCTGTGG
GCTCCACGGGAGCCAGTGCCGCAGGGGCAGGTTGAAGTCCTGCAACTGGATGTGGGGCAGGGCCTGGCCGTGCTGCTGCG
AACCCGCACGCACAGCCTGCTTTACGATGCCGGCCCCGCCAAGGGTGACATGGACCTGGGGGACCGGGTGGTGTTGCCGA
CCTTGCGCAAGCTTGGCGTCAAGCACCTGGATCTGATGCTGATCAGTCATGGCCACGCCGATCATGCCGGCGGCGCAGCG
GCTATCGGGCGCGGTCTGCCGCTGGGTAGGGTGCTTGCGGGGGAGCCTGAACAATTACCGGAGGCTTTGCGGGCACGCCG
GTGCGTCAGTGGCGAGCGCTGGCACTGGGATGGGGTGGACTTCATGCTTTGGCAGTGGGCAGGGGGACCGGCCGGTAACG
AGCGTTCCTGTGCGCTGCTGGTACAGGCCCAGGGCGAGCGGTTGTTACTGGCCGGCGATATGGAGGCTGGTGCCGAGCGG
GCTTGGCTGGCAGCGACCGATGCGCCGCGCATCGACTGGTTGCAGGCGCCGCACCATGGCAGTCGCAGCTCGTCCACCGA
GCCGTTCATCCGCGCTACGTCGCCAAGGGGCGTGATGATTTCCCGGGGGCGTTACAACAGCTTCGGTCATCCGCATCCGC
AGGTCGTGGAGCGTTACCGGCGGTACGGGTTGAGCGTTCATGACACCGCGATCGAAGGCGCTTTGCGCCTACGCCTGGGC
ACCCATGGCGAGGTCGAGGGACTGCGGGCGCAGCGGCGGTTCTGGCGACAGGTGCAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (25-166)

• Metallo-beta-lactamase superfamily (Lactamase_B) (497-675)

• Competence protein (Competence) (198-464)

3D structure

• AlphaFold DB: A0A6S5U108

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.554	97.294	0.57
comA	Ralstonia pseudosolanacearum GMI1000	35.058	100	0.367