Detailed information NTG0770244

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: PCP48_RS10405
• Genome accession: NZ_CP115248
• Coordinates: 2189989..2192214 (+)
• Length: 741 a.a.
• NCBI ID: WP_003113988.1
• Uniprot ID: Q9HZM0
• Organism: Pseudomonas aeruginosa strain F038
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2184989..2197214

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PCP48_RS10380 (PCP48_10370)	-	2185295..2185894 (-)	600	WP_003105196.1	PilZ domain-containing protein	-
PCP48_RS10385 (PCP48_10375)	-	2185997..2187247 (+)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
PCP48_RS10390 (PCP48_10380)	lolD	2187240..2187923 (+)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
PCP48_RS10395 (PCP48_10385)	-	2187993..2189237 (+)	1245	WP_023085389.1	lipoprotein-releasing ABC transporter permease subunit	-
PCP48_RS10400 (PCP48_10390)	-	2189325..2189858 (-)	534	WP_003091165.1	DUF2062 domain-containing protein	-
PCP48_RS10405 (PCP48_10395)	comA	2189989..2192214 (+)	2226	WP_003113988.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PCP48_RS10410 (PCP48_10400)	exbB	2192287..2192922 (+)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
PCP48_RS10415 (PCP48_10405)	-	2192919..2193359 (+)	441	WP_003091161.1	ExbD/TolR family protein	-
PCP48_RS10420 (PCP48_10410)	lpxK	2193359..2194357 (+)	999	WP_025271185.1	tetraacyldisaccharide 4'-kinase	-
PCP48_RS10425 (PCP48_10415)	-	2194395..2194580 (+)	186	WP_003091157.1	Trm112 family protein	-
PCP48_RS10430 (PCP48_10420)	kdsB	2194580..2195344 (+)	765	WP_003130694.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
PCP48_RS10435 (PCP48_10425)	-	2195344..2195808 (+)	465	WP_033983129.1	low molecular weight protein-tyrosine-phosphatase	-
PCP48_RS10440 (PCP48_10430)	murB	2195805..2196824 (+)	1020	WP_025271183.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79979.60 Da
• Isoelectric Point: 10.3506

>NTDB_id=770244 PCP48_RS10405 WP_003113988.1 2189989..2192214(+) (comA) [Pseudomonas aeruginosa strain F038]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHVLLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPVWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=770244 PCP48_RS10405 WP_003113988.1 2189989..2192214(+) (comA) [Pseudomonas aeruginosa strain F038]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTTGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGGTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCCGTG
GGCACGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGACGCCTGGCGCCAACGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGCATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCAGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGCGCCTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTGTGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCATTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGAGAGCATGTCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGTTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCACAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: Q9HZM0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.807	97.301	0.572
comA	Ralstonia pseudosolanacearum GMI1000	35.611	100	0.366