Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   LL303_RS02400 Genome accession   NZ_CP126467
Coordinates   446099..447541 (-) Length   480 a.a.
NCBI ID   WP_010905315.1    Uniprot ID   Q9CIG6
Organism   Lactococcus lactis subsp. lactis strain 303     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 441099..452541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL303_RS02375 (LL303_02380) nox 441131..442471 (+) 1341 WP_023163754.1 H2O-forming NADH oxidase -
  LL303_RS02380 (LL303_02385) - 442561..442950 (+) 390 WP_023163755.1 single-stranded DNA-binding protein -
  LL303_RS02385 (LL303_02390) groES 443070..443354 (+) 285 WP_003131589.1 co-chaperone GroES -
  LL303_RS02390 (LL303_02395) groL 443442..445070 (+) 1629 WP_003131585.1 chaperonin GroEL -
  LL303_RS02395 (LL303_02400) vicX 445116..445928 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  LL303_RS02400 (LL303_02405) vicK 446099..447541 (-) 1443 WP_010905315.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LL303_RS02405 (LL303_02410) yycF 447534..448235 (-) 702 WP_003131580.1 response regulator YycF -
  LL303_RS02410 (LL303_02415) tmk 448413..449048 (+) 636 WP_012897230.1 dTMP kinase -
  LL303_RS02415 (LL303_02420) - 449181..450041 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  LL303_RS02420 (LL303_02425) yaaT 450093..450875 (+) 783 WP_010905316.1 stage 0 sporulation family protein Regulator
  LL303_RS02425 (LL303_02430) yabA 450868..451194 (+) 327 WP_003131570.1 DNA replication initiation control protein YabA -
  LL303_RS02430 (LL303_02435) rsmI 451194..452069 (+) 876 WP_010905318.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  LL303_RS02435 (LL303_02440) - 452146..452337 (-) 192 WP_003131566.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54695.14 Da        Isoelectric Point: 4.5889

>NTDB_id=767330 LL303_RS02400 WP_010905315.1 446099..447541(-) (vicK) [Lactococcus lactis subsp. lactis strain 303]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKITDQYNFYDLLEKEPEITIETHDSGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=767330 LL303_RS02400 WP_010905315.1 446099..447541(-) (vicK) [Lactococcus lactis subsp. lactis strain 303]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTACTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATTC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGGATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
TATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CIG6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442