Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   OIY87_RS10465 Genome accession   NZ_CP113954
Coordinates   2087387..2088118 (-) Length   243 a.a.
NCBI ID   WP_269724978.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain XH2168     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2082387..2093118
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OIY87_RS10420 (OIY87_11735) comE/comE2 2082848..2083576 (-) 729 WP_012962512.1 LytR/AlgR family response regulator transcription factor Regulator
  OIY87_RS10425 (OIY87_11740) - 2083675..2083968 (-) 294 WP_252521385.1 bacteriocin immunity protein -
  OIY87_RS10430 (OIY87_11745) - 2084019..2084171 (-) 153 WP_231873055.1 hypothetical protein -
  OIY87_RS10435 (OIY87_11750) - 2084518..2084829 (-) 312 WP_269724974.1 bacteriocin immunity protein -
  OIY87_RS10440 (OIY87_11755) - 2084841..2084990 (-) 150 WP_269724975.1 bacteriocin -
  OIY87_RS10445 (OIY87_11760) - 2085075..2085299 (-) 225 WP_269724976.1 DUF3884 family protein -
  OIY87_RS10450 (OIY87_11765) - 2085410..2085625 (-) 216 WP_074658217.1 hypothetical protein -
  OIY87_RS10455 (OIY87_11770) - 2085913..2086050 (+) 138 WP_009854999.1 hypothetical protein -
  OIY87_RS10460 (OIY87_11775) - 2086072..2087379 (-) 1308 WP_269724977.1 sensor histidine kinase -
  OIY87_RS10465 (OIY87_11780) comE/comE1 2087387..2088118 (-) 732 WP_269724978.1 response regulator transcription factor Regulator
  OIY87_RS10470 (OIY87_11785) - 2088135..2088461 (-) 327 WP_009855002.1 LytTR family DNA-binding domain-containing protein -
  OIY87_RS10475 (OIY87_11790) - 2088645..2089937 (-) 1293 WP_013643489.1 glycosyltransferase family 2 protein -
  OIY87_RS10480 (OIY87_11795) - 2089939..2090238 (-) 300 WP_013643490.1 DUF3884 family protein -
  OIY87_RS10485 (OIY87_11800) - 2090264..2090446 (-) 183 WP_013643491.1 hypothetical protein -
  OIY87_RS10490 (OIY87_11805) - 2090528..2090737 (-) 210 WP_013643492.1 helix-turn-helix domain-containing protein -
  OIY87_RS10495 (OIY87_11810) - 2090727..2091740 (-) 1014 WP_269724979.1 bacteriocin biosynthesis protein -
  OIY87_RS10500 (OIY87_11815) - 2092799..2092996 (-) 198 WP_009855009.1 class IIb bacteriocin, lactobin A/cerein 7B family -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28484.66 Da        Isoelectric Point: 5.4335

>NTDB_id=763846 OIY87_RS10465 WP_269724978.1 2087387..2088118(-) (comE/comE1) [Streptococcus gallolyticus strain XH2168]
MLDIYVLEDNIIQQFRMEREIATIMAKNNWDYQRIEVFSSANEIIAKATEKGEHQIFFLDLEIRDDEKQGIDVAKAIREK
DATAIIVFVTTHSEFMLLTYQALVGAIDFIDKNLNDQVFSERIELCLKEAMKHQNDNFGENSFLFETPKARVRMPYSDIL
YFETSPAVHRVIMHTKNDRMEFYATIAEIAKSDKRLFKCHRSFIINVDNVVRFDKATRSVYFETGDTCLVSRDKIKPLLN
EMR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=763846 OIY87_RS10465 WP_269724978.1 2087387..2088118(-) (comE/comE1) [Streptococcus gallolyticus strain XH2168]
ATGTTAGATATTTATGTACTAGAGGATAATATCATACAGCAATTTCGTATGGAACGCGAGATTGCGACCATTATGGCAAA
AAATAATTGGGACTATCAGAGAATAGAGGTGTTTAGTTCCGCAAATGAGATTATAGCTAAGGCAACTGAAAAAGGGGAGC
ATCAAATTTTCTTTCTTGATTTAGAAATCAGAGACGACGAAAAACAAGGAATTGACGTCGCTAAAGCTATTCGTGAAAAA
GATGCAACAGCTATCATTGTTTTTGTAACAACTCATTCAGAATTTATGCTGCTGACCTACCAAGCGTTAGTAGGGGCAAT
TGATTTTATTGATAAGAACCTGAATGACCAAGTATTTAGTGAACGCATAGAGTTGTGCCTAAAGGAAGCCATGAAACATC
AAAATGATAATTTCGGCGAAAATTCCTTTTTATTTGAAACTCCTAAAGCACGTGTACGCATGCCATATAGTGATATTCTC
TATTTTGAAACCTCTCCTGCTGTGCACCGCGTGATTATGCATACAAAAAATGACAGAATGGAATTTTATGCAACGATTGC
AGAGATTGCTAAATCAGACAAACGTCTTTTTAAGTGTCACCGTTCTTTTATCATTAATGTGGATAATGTGGTCAGATTTG
ATAAAGCGACACGAAGTGTTTATTTCGAAACTGGGGACACTTGCCTAGTTTCTAGAGATAAAATAAAACCTCTATTAAAT
GAGATGAGGTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(11-123)

LytTr DNA-binding domain (LytTR)

(152-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

71.193

100

0.712
  comE/blpR Streptococcus mutans UA159

47.699

98.354

0.469
  comE/comE2 Streptococcus equinus JB1

46.281

99.588

0.461