Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   OIY87_RS09570 Genome accession   NZ_CP113954
Coordinates   1912819..1913511 (-) Length   230 a.a.
NCBI ID   WP_009854820.1    Uniprot ID   A0A139QWD3
Organism   Streptococcus gallolyticus strain XH2168     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1907819..1918511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OIY87_RS09550 (OIY87_10865) dnaI 1908594..1909496 (-) 903 WP_268712247.1 primosomal protein DnaI -
  OIY87_RS09555 (OIY87_10870) - 1909507..1910664 (-) 1158 WP_269724932.1 DnaD domain protein -
  OIY87_RS09560 (OIY87_10875) nrdR 1910648..1911145 (-) 498 WP_009854818.1 transcriptional regulator NrdR -
  OIY87_RS09565 (OIY87_10880) - 1911335..1912819 (-) 1485 WP_012962415.1 sensor histidine kinase -
  OIY87_RS09570 (OIY87_10885) covR 1912819..1913511 (-) 693 WP_009854820.1 response regulator transcription factor Regulator
  OIY87_RS09575 (OIY87_10890) - 1913749..1914285 (-) 537 WP_043878598.1 DUF177 domain-containing protein -
  OIY87_RS09580 (OIY87_10895) htpX 1914427..1915329 (-) 903 WP_009854824.1 zinc metalloprotease HtpX -
  OIY87_RS09585 (OIY87_10900) - 1915456..1916007 (-) 552 WP_012962418.1 LemA family protein -
  OIY87_RS09590 (OIY87_10905) rsmG 1916338..1917051 (+) 714 WP_247945821.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  OIY87_RS09595 (OIY87_10910) - 1917121..1918494 (+) 1374 WP_247945808.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26487.39 Da        Isoelectric Point: 4.7059

>NTDB_id=763840 OIY87_RS09570 WP_009854820.1 1912819..1913511(-) (covR) [Streptococcus gallolyticus strain XH2168]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDVESKREQDSQGKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=763840 OIY87_RS09570 WP_009854820.1 1912819..1913511(-) (covR) [Streptococcus gallolyticus strain XH2168]
ATGAGTAAAAAGATTTTAATTATTGAAGATGAAAAAAATCTTGCACGCTTTGTGTCTTTGGAGTTACAACATGAAGGTTA
TTCTGTAGTTGTAGAAACAAACGGGCGCTTAGGGCTTCAAACGGCTCTTGATGACGATTTTGACTTGATTTTGCTTGATT
TAATGCTTCCAGATATGGATGGATTTGAAATCACGCGTCGTCTTCGATTGGAAAAAGAAACTTCTATTATTATGATGACA
GCTCGTGACTCTATTATGGATATTGTTGCTGGGCTTGATCGTGGTGCAGATGACTATATTGTCAAACCATTTGCAATTGA
AGAACTCTTGGCTCGTGTTCGTGCTGTTTTCCGCCGTCAAGACGTTGAATCTAAACGTGAACAAGACAGTCAAGGAAAAG
AAGGATTGCTTGGTCTACGCTTAAATCCTCAAAATCGTTCAGCGGTTCGAGGTGATGATGAAATTTCGCTTACAAAACGT
GAGTACGATTTGTTAAGTGTTCTTTTGTCAAATGTTAATCGTGTAATGACACGTGAAGAACTGCTAGCCAGTGTTTGGAG
ATACGATACAGATATTGAGACAAATGTTGTTGATGTTTATATCCGTTACCTTCGCGGAAAAGTCGATATTCCAGGTAAAG
AATCTTACATTCAAACAGTTCGTGGAATGGGATACATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139QWD3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

75.217

100

0.752
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.755

99.565

0.635
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.422