Detailed information NTG0762463

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: OPT59_RS00755
• Genome accession: NZ_CP125360
• Coordinates: 122604..123044 (+)
• Length: 146 a.a.
• NCBI ID: WP_003061780.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain UT_120444
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 117604..128044

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OPT59_RS00725 (OPT59_00725)	-	119285..119650 (+)	366	WP_003055257.1	DUF1033 family protein	-
OPT59_RS00730 (OPT59_00730)	comGA/cglA	119731..120672 (+)	942	WP_015016543.1	competence type IV pilus ATPase ComGA	Machinery gene
OPT59_RS00735 (OPT59_00735)	comGB	120608..121639 (+)	1032	WP_042357807.1	competence type IV pilus assembly protein ComGB	Machinery gene
OPT59_RS00740 (OPT59_00740)	comGC	121641..121967 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
OPT59_RS00745 (OPT59_00745)	comGD	121942..122370 (+)	429	WP_041788719.1	competence type IV pilus minor pilin ComGD	Machinery gene
OPT59_RS00750 (OPT59_00750)	comGE	122378..122623 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
OPT59_RS00755 (OPT59_00755)	comGF	122604..123044 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
OPT59_RS00760 (OPT59_00760)	comGG	123022..123396 (+)	375	WP_012766449.1	competence type IV pilus minor pilin ComGG	-
OPT59_RS00765 (OPT59_00765)	comGH	123459..124412 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
OPT59_RS00770 (OPT59_00770)	-	124471..125667 (+)	1197	WP_003058485.1	acetate kinase	-
OPT59_RS00775 (OPT59_00775)	-	125973..126179 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
OPT59_RS00780 (OPT59_00780)	-	126282..126962 (+)	681	WP_003060329.1	type II CAAX endopeptidase family protein	-
OPT59_RS00785 (OPT59_00785)	-	126980..127417 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16969.55 Da
• Isoelectric Point: 10.6305

>NTDB_id=762463 OPT59_RS00755 WP_003061780.1 122604..123044(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=762463 OPT59_RS00755 WP_003061780.1 122604..123044(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.921	95.205	0.466
comGF	Streptococcus mutans UA140	48.201	95.205	0.459
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411