Detailed information NTG0762290

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: OQG81_RS03955
• Genome accession: NZ_CP113440
• Coordinates: 709778..712009 (+)
• Length: 743 a.a.
• NCBI ID: WP_014294208.1
• Uniprot ID: A0AA47FDQ0
• Organism: Streptococcus macedonicus strain E37
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 704778..717009

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OQG81_RS03930 (OQG81_03930)	-	705540..707120 (+)	1581	WP_014294203.1	DEAD/DEAH box helicase	-
OQG81_RS03935 (OQG81_03935)	-	707163..707435 (-)	273	WP_014294204.1	GIY-YIG nuclease family protein	-
OQG81_RS03940 (OQG81_03940)	-	707410..708171 (-)	762	WP_014294205.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
OQG81_RS03945 (OQG81_03945)	-	708279..709025 (+)	747	WP_014294206.1	lysophospholipid acyltransferase family protein	-
OQG81_RS03950 (OQG81_03950)	comEA	709120..709785 (+)	666	WP_014294207.1	helix-hairpin-helix domain-containing protein	Machinery gene
OQG81_RS03955 (OQG81_03955)	comEC/celB	709778..712009 (+)	2232	WP_014294208.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
OQG81_RS03960 (OQG81_03960)	holA	712081..713118 (+)	1038	WP_039670612.1	DNA polymerase III subunit delta	-
OQG81_RS03965 (OQG81_03965)	sodA	713207..713815 (+)	609	WP_014294210.1	superoxide dismutase SodA	-
OQG81_RS03970 (OQG81_03970)	-	713966..714691 (+)	726	WP_014294211.1	YebC/PmpR family DNA-binding transcriptional regulator	-
OQG81_RS03975 (OQG81_03975)	queA	714723..715751 (-)	1029	WP_014294212.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
OQG81_RS03980 (OQG81_03980)	-	715968..716426 (+)	459	WP_223246245.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 84044.59 Da
• Isoelectric Point: 8.8509

>NTDB_id=762290 OQG81_RS03955 WP_014294208.1 709778..712009(+) (comEC/celB) [Streptococcus macedonicus strain E37]
MIKYFPIKPIQLAFLLILLYYFCFSKVIGCLMFLLLVLVFLWQQYGWKAWCQVCLCLSCFAVFFLTKSNQTEQAYQVVPA
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLNQTIVLSGDMDLEEATPQRNFGGFDYRTYLKH
EGIYRVVNLSAINNVELVYKMTLWDKLHDVRRKAIVSIQRHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGTFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGYSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFMVMPN
FLLTTGGILSFTYAFILSFIDFNDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSIIF
ILSPLVKLTCFNGCFVFLETVIKNTKVILGGPIVFGKPSLGILVLLFLTLGVLYDCWRRKKMAIFLVSLVVLLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKHVKIGKVLVSQGSLTKPDFVAKLQAMKTKVRVVTASDVLPIMGSYLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELVATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=762290 OQG81_RS03955 WP_014294208.1 709778..712009(+) (comEC/celB) [Streptococcus macedonicus strain E37]
TTGATTAAGTATTTTCCTATTAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAAAGT
GATTGGGTGTTTGATGTTTCTCTTGCTAGTCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAAGTTT
GTTTGTGTTTAAGCTGTTTTGCGGTATTTTTTCTGACTAAGTCTAATCAGACAGAGCAGGCTTATCAAGTAGTGCCAGCT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGAGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCGGAGAAAGAACAGCATTTTTTTAAGACATTAAATCAAACGATTGTTT
TATCTGGTGATATGGACTTGGAAGAAGCAACGCCCCAGCGGAATTTTGGTGGTTTTGATTATCGTACTTACCTTAAACAT
GAAGGCATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTTATAAGATGACTTTGTGGGATAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCGGCATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGTATGCAGGTCGGATTTTTTGTGGGGACATTCCGATTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
TATACTACAAATCCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTATTCTGTTTCGGTGATTCGGAGTTTAATTCAAT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTGGCTTTAACTTTGTTTGTTCTTTTCATGGTTATGCCAAAT
TTTTTACTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTGACTTTAATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACAGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGTTATCAATCATTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTTTTGGAAACTGTTATCAAGAACACTAAGGT
AATTTTGGGCGGTCCGATTGTTTTTGGGAAACCAAGTCTTGGTATCTTGGTGCTACTATTTTTAACATTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAATGGCAATTTTTCTTGTCAGCTTAGTAGTTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACAGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGCATACGCTGCT
AATTGATGTGGGTGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGCTGACGGATAGTAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAGGTGGCGAAACACGTAAAAATTGGTAAAGTGCTGGTGAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTAGTGATGTTTTGCCGATTATGGGAAGTTACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTATTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTGGTTGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGGCATCATGGCTCAAAAGGGTCATCAAGCTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTAA
TTTCCGCAGGGCAAAATAACCGCTACAAACATCCTCATCAAGAGACACTTGAACGCTTCCGAGCACAAAACATGACCATT
TACCGCACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (213-459)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.022	99.865	0.52
comEC/celB	Streptococcus mitis SK321	51.482	99.865	0.514
comEC/celB	Streptococcus pneumoniae TIGR4	50.471	100	0.505
comEC/celB	Streptococcus pneumoniae Rx1	49.933	100	0.499
comEC/celB	Streptococcus pneumoniae D39	49.933	100	0.499
comEC/celB	Streptococcus pneumoniae R6	49.933	100	0.499
comEC	Lactococcus lactis subsp. cremoris KW2	47.715	100	0.478