Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   OTB22_RS10720 Genome accession   NZ_CP113267
Coordinates   2095730..2096392 (-) Length   220 a.a.
NCBI ID   WP_050201094.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2090730..2101392
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTB22_RS10695 (OTB22_10700) - 2090880..2091146 (-) 267 WP_001278167.1 Veg family protein -
  OTB22_RS10700 (OTB22_10705) dnaB 2091148..2092500 (-) 1353 WP_000852486.1 replicative DNA helicase -
  OTB22_RS10705 (OTB22_10710) rplI 2092544..2092996 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  OTB22_RS10710 (OTB22_10715) - 2092993..2094966 (-) 1974 WP_044790958.1 DHH family phosphoesterase -
  OTB22_RS10715 (OTB22_10720) hpf 2095102..2095650 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  OTB22_RS10720 (OTB22_10725) comFC/cflB 2095730..2096392 (-) 663 WP_050201094.1 ComF family protein Machinery gene
  OTB22_RS10725 (OTB22_10730) comFA/cflA 2096389..2097687 (-) 1299 WP_000867608.1 DEAD/DEAH box helicase Machinery gene
  OTB22_RS10730 (OTB22_10735) - 2097743..2098378 (+) 636 WP_000395739.1 YigZ family protein -
  OTB22_RS10735 (OTB22_10740) cysK 2098663..2099583 (+) 921 WP_000029860.1 cysteine synthase A -
  OTB22_RS10740 (OTB22_10745) - 2099658..2100196 (-) 539 Protein_2085 IS66 family transposase -
  OTB22_RS10745 (OTB22_10750) - 2100169..2100477 (+) 309 Protein_2086 transposase -
  OTB22_RS10750 (OTB22_10755) tnpB 2100618..2100941 (-) 324 WP_000973416.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25271.12 Da        Isoelectric Point: 7.3688

>NTDB_id=761524 OTB22_RS10720 WP_050201094.1 2095730..2096392(-) (comFC/cflB) [Streptococcus pneumoniae strain BC2]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEATGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=761524 OTB22_RS10720 WP_050201094.1 2095730..2096392(-) (comFC/cflB) [Streptococcus pneumoniae strain BC2]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAACAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(152-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909