Detailed information NTG0761461

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: OTB22_RS01990
• Genome accession: NZ_CP113267
• Coordinates: 380653..381312 (-)
• Length: 219 a.a.
• NCBI ID: WP_000565027.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BC2
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	382056..390349	380653..381312	flank	744

Gene organization within MGE regions

Location: 380653..390349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OTB22_RS01990 (OTB22_01995)	cclA/cilC	380653..381312 (-)	660	WP_000565027.1	prepilin peptidase	Machinery gene
OTB22_RS01995 (OTB22_02000)	-	381382..381828 (+)	447	WP_000155408.1	GNAT family N-acetyltransferase	-
OTB22_RS02000 (OTB22_02005)	-	382056..383234 (-)	1179	WP_000175880.1	ROK family transcriptional regulator	-
OTB22_RS02005 (OTB22_02010)	-	383514..384776 (+)	1263	WP_000413336.1	PTS sugar transporter subunit IIC	-
OTB22_RS02010 (OTB22_02015)	-	384779..385675 (+)	897	WP_000825667.1	PEP phosphonomutase	-
OTB22_RS02015 (OTB22_02020)	-	385690..386007 (+)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
OTB22_RS02020 (OTB22_02025)	-	386024..386341 (+)	318	WP_001005885.1	PTS lactose/cellobiose transporter subunit IIA	-
OTB22_RS02025 (OTB22_02030)	-	386351..387706 (+)	1356	WP_001094996.1	PTS sugar transporter subunit IIC	-
OTB22_RS02030 (OTB22_02035)	-	388029..389504 (+)	1476	WP_000250870.1	arylsulfatase	-
OTB22_RS02035 (OTB22_02040)	-	389501..390349 (+)	849	WP_000782429.1	formylglycine-generating enzyme family protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24855.00 Da
• Isoelectric Point: 7.2564

>NTDB_id=761461 OTB22_RS01990 WP_000565027.1 380653..381312(-) (cclA/cilC) [Streptococcus pneumoniae strain BC2]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSVSHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=761461 OTB22_RS01990 WP_000565027.1 380653..381312(-) (cclA/cilC) [Streptococcus pneumoniae strain BC2]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGTCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAGTTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae D39	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae R6	97.26	100	0.973
cclA/cilC	Streptococcus pneumoniae TIGR4	96.804	100	0.968
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	85.845	100	0.858