Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   OS912_RS04025 Genome accession   NZ_CP113266
Coordinates   815000..815659 (+) Length   219 a.a.
NCBI ID   WP_268233020.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC1     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 810000..820659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS04000 (OS912_04005) - 810305..810622 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  OS912_RS04005 (OS912_04010) - 810637..811533 (-) 897 WP_000825669.1 PEP phosphonomutase -
  OS912_RS04010 (OS912_04015) - 811536..812798 (-) 1263 WP_268233019.1 PTS sugar transporter subunit IIC -
  OS912_RS04015 (OS912_04020) - 813078..814256 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  OS912_RS04020 (OS912_04025) - 814484..814930 (-) 447 WP_000155414.1 GNAT family N-acetyltransferase -
  OS912_RS04025 (OS912_04030) cclA/cilC 815000..815659 (+) 660 WP_268233020.1 prepilin peptidase Machinery gene
  OS912_RS04030 (OS912_04035) - 815711..816862 (-) 1152 WP_050135960.1 XRE family transcriptional regulator -
  OS912_RS04035 (OS912_04040) - 816877..817608 (-) 732 WP_000934017.1 hypothetical protein -
  OS912_RS04040 (OS912_04045) - 817828..817938 (+) 111 Protein_809 prepilin peptidase -
  OS912_RS04045 (OS912_04050) trpA 817910..818686 (-) 777 WP_044788824.1 tryptophan synthase subunit alpha -
  OS912_RS04050 (OS912_04055) trpB 818679..819902 (-) 1224 WP_000331287.1 tryptophan synthase subunit beta -
  OS912_RS04055 (OS912_04060) - 819880..820479 (-) 600 WP_050135957.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24839.95 Da        Isoelectric Point: 7.6640

>NTDB_id=761392 OS912_RS04025 WP_268233020.1 815000..815659(+) (cclA/cilC) [Streptococcus pneumoniae strain BC1]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHFDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=761392 OS912_RS04025 WP_268233020.1 815000..815659(+) (cclA/cilC) [Streptococcus pneumoniae strain BC1]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTTCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACTGCTGGTTTGACCTTGGGTAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTTCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae D39

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae R6

97.717

100

0.977
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

88.128

100

0.881