Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   OTU47_RS02185 Genome accession   NZ_CP113115
Coordinates   427305..427541 (-) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP2     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 422305..432541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU47_RS02155 (OTU47_02155) radA 422599..423960 (-) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene
  OTU47_RS02160 (OTU47_02160) - 423974..424489 (-) 516 WP_000691236.1 histidine phosphatase family protein -
  OTU47_RS02165 (OTU47_02165) - 424491..424934 (-) 444 WP_000701994.1 dUTP diphosphatase -
  OTU47_RS02175 (OTU47_02175) tadA 425120..425587 (-) 468 WP_000291875.1 tRNA adenosine(34) deaminase TadA -
  OTU47_RS02180 (OTU47_02180) - 425788..427074 (-) 1287 WP_000205044.1 adenylosuccinate synthase -
  OTU47_RS02185 (OTU47_02185) comW 427305..427541 (-) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  OTU47_RS02190 (OTU47_02190) - 427806..428579 (+) 774 Protein_435 transposase -

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=760393 OTU47_RS02185 WP_000939546.1 427305..427541(-) (comW) [Streptococcus pneumoniae strain NP2]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=760393 OTU47_RS02185 WP_000939546.1 427305..427541(-) (comW) [Streptococcus pneumoniae strain NP2]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGGTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987

  comW Streptococcus pneumoniae D39

98.718

100

0.987

  comW Streptococcus pneumoniae R6

98.718

100

0.987

  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756