Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   OTU45_RS11115 Genome accession   NZ_CP113114
Coordinates   2133900..2134916 (-) Length   338 a.a.
NCBI ID   WP_012512625.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2128900..2139916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS11070 (OTU45_11070) - 2129228..2129416 (-) 189 WP_001161207.1 helix-turn-helix transcriptional regulator -
  OTU45_RS11075 (OTU45_11075) - 2129608..2129898 (-) 291 WP_001815531.1 hypothetical protein -
  OTU45_RS11080 (OTU45_11080) - 2130097..2130546 (+) 450 WP_001058908.1 hypothetical protein -
  OTU45_RS11085 (OTU45_11085) - 2130537..2130704 (-) 168 WP_267748061.1 hypothetical protein -
  OTU45_RS11090 (OTU45_11090) - 2130779..2131054 (-) 276 WP_001094375.1 hypothetical protein -
  OTU45_RS11095 (OTU45_11095) - 2131209..2131997 (+) 789 WP_050116194.1 helix-turn-helix domain-containing protein -
  OTU45_RS11100 (OTU45_11100) - 2131999..2132199 (+) 201 WP_000064302.1 hypothetical protein -
  OTU45_RS11105 (OTU45_11105) - 2132373..2133818 (+) 1446 WP_267748066.1 recombinase family protein -
  OTU45_RS11115 (OTU45_11115) comGB/cglB 2133900..2134916 (-) 1017 WP_012512625.1 competence type IV pilus assembly protein ComGB Machinery gene
  OTU45_RS11120 (OTU45_11120) comGA/cglA/cilD 2134864..2135805 (-) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  OTU45_RS11125 (OTU45_11125) - 2135881..2136246 (-) 366 WP_000286415.1 DUF1033 family protein -
  OTU45_RS11130 (OTU45_11130) - 2136397..2137455 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  OTU45_RS11135 (OTU45_11135) nagA 2137618..2138769 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38524.56 Da        Isoelectric Point: 9.6162

>NTDB_id=760377 OTU45_RS11115 WP_012512625.1 2133900..2134916(-) (comGB/cglB) [Streptococcus pneumoniae strain NP1]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LVMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=760377 OTU45_RS11115 WP_012512625.1 2133900..2134916(-) (comGB/cglB) [Streptococcus pneumoniae strain NP1]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGTCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae D39

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae R6

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae TIGR4

98.225

100

0.982
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

93.787

100

0.938
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

57.595

93.491

0.538
  comYB Streptococcus mutans UA159

57.595

93.491

0.538
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503