Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   OTU45_RS00380 Genome accession   NZ_CP113114
Coordinates   69983..70219 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP1     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 64983..75219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS00375 (OTU45_00375) - 68945..69718 (-) 774 Protein_63 transposase -
  OTU45_RS00380 (OTU45_00380) comW 69983..70219 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  OTU45_RS00385 (OTU45_00385) - 70450..71736 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  OTU45_RS00390 (OTU45_00390) tadA 71937..72404 (+) 468 WP_000291875.1 tRNA adenosine(34) deaminase TadA -
  OTU45_RS00400 (OTU45_00400) - 72590..73033 (+) 444 WP_000701994.1 dUTP diphosphatase -
  OTU45_RS00405 (OTU45_00405) - 73035..73550 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  OTU45_RS00410 (OTU45_00410) radA 73564..74925 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=760314 OTU45_RS00380 WP_000939546.1 69983..70219(+) (comW) [Streptococcus pneumoniae strain NP1]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=760314 OTU45_RS00380 WP_000939546.1 69983..70219(+) (comW) [Streptococcus pneumoniae strain NP1]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGGTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987
  comW Streptococcus pneumoniae D39

98.718

100

0.987
  comW Streptococcus pneumoniae R6

98.718

100

0.987
  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987
  comW Streptococcus mitis SK321

76.923

100

0.769
  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756