NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	ORM95_RS23610	Genome accession	NZ_CP111101
Coordinates	4593823..4594947 (+)	Length	374 a.a.
NCBI ID	WP_000228544.1	Uniprot ID	A0A9P2PX49
Organism	Escherichia coli strain FRIK1989
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 4588823..4599947

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ORM95_RS23585 (ORM95_23465)	mscL	4588949..4589359 (-)	411	WP_000022440.1	large-conductance mechanosensitive channel protein MscL	-
ORM95_RS23590 (ORM95_23470)	trkA	4589489..4590865 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
ORM95_RS23595 (ORM95_23475)	rsmB	4590887..4592176 (-)	1290	WP_001301795.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
ORM95_RS23600 (ORM95_23480)	fmt	4592222..4593169 (-)	948	WP_000004459.1	methionyl-tRNA formyltransferase	-
ORM95_RS23605 (ORM95_23485)	def	4593184..4593693 (-)	510	WP_000114984.1	peptide deformylase	-
ORM95_RS23610 (ORM95_23490)	dprA	4593823..4594947 (+)	1125	WP_000228544.1	DNA-protecting protein DprA	Machinery gene
ORM95_RS23615 (ORM95_23495)	smg	4594919..4595392 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
ORM95_RS23620 (ORM95_23500)	yrdD	4595421..4595963 (+)	543	WP_001129722.1	type I DNA topoisomerase	-
ORM95_RS23625 (ORM95_23505)	tsaC	4595968..4596540 (+)	573	WP_001301437.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
ORM95_RS23630 (ORM95_23510)	aroE	4596545..4597363 (+)	819	WP_000451254.1	shikimate dehydrogenase	-
ORM95_RS23635 (ORM95_23515)	yrdB	4597360..4597617 (+)	258	WP_001070590.1	DUF1488 domain-containing protein	-
ORM95_RS23640 (ORM95_23520)	yrdA	4597593..4598147 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 41005.96 Da Isoelectric Point: 6.2655

                                >NTDB_id=757887 ORM95_RS23610 WP_000228544.1 4593823..4594947(+) (dprA) [Escherichia coli strain FRIK1989]

MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=757887 ORM95_RS23610 WP_000228544.1 4593823..4594947(+) (dprA) [Escherichia coli strain FRIK1989]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT

TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.78	98.663	0.481
dprA	Glaesserella parasuis strain SC1401	45.401	90.107	0.409
dprA	Vibrio cholerae strain A1552	49.355	82.888	0.409
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	44.545	88.235	0.393

Detailed information NTG0757887