Detailed information
Bioinformatically predicted
Overview
| Name | ciaH | Type | Regulator |
| Locus tag | UKS_RS03915 | Genome accession | NZ_AP021887 |
| Coordinates | 757099..758433 (+) | Length | 444 a.a. |
| NCBI ID | WP_156011884.1 | Uniprot ID | - |
| Organism | Streptococcus sp. 116-D4 | ||
| Function | repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation |
||
Genomic Context
Location: 752099..763433
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| UKS_RS03895 (UKS_07200) | - | 752269..753153 (+) | 885 | WP_173020456.1 | putative PEP-binding protein | - |
| UKS_RS03900 (UKS_07210) | - | 753113..753553 (+) | 441 | WP_156011882.1 | ASCH domain-containing protein | - |
| UKS_RS03905 (UKS_07220) | - | 753675..756221 (+) | 2547 | WP_156011883.1 | M1 family metallopeptidase | - |
| UKS_RS03910 (UKS_07230) | ciaR | 756435..757109 (+) | 675 | WP_000590639.1 | two-component system response regulator CiaR | Regulator |
| UKS_RS03915 (UKS_07240) | ciaH | 757099..758433 (+) | 1335 | WP_156011884.1 | two-component system sensor histidine kinase CiaH | Regulator |
| UKS_RS03920 (UKS_07250) | - | 758467..758754 (-) | 288 | WP_156011885.1 | DUF3270 domain-containing protein | - |
| UKS_RS03925 (UKS_07260) | - | 759112..760167 (+) | 1056 | WP_156011886.1 | ABC transporter permease | - |
| UKS_RS03930 (UKS_07270) | - | 760181..760861 (+) | 681 | WP_156011887.1 | ABC transporter ATP-binding protein | - |
| UKS_RS03935 (UKS_07280) | - | 761101..762030 (+) | 930 | WP_156011888.1 | peptidase U32 family protein | - |
Sequence
Protein
Download Length: 444 a.a. Molecular weight: 50649.39 Da Isoelectric Point: 9.1662
>NTDB_id=75350 UKS_RS03915 WP_156011884.1 757099..758433(+) (ciaH) [Streptococcus sp. 116-D4]
MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDTLHGLSKNPQAVIQLAINRATEEIKDLENAA
TDTSKTEVKPNVSSNTEVILLDKNFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRMILMETNISSVSTN
IKYAAVLINTSQLEQASQKHEQLIVIVMASFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE
TLFRKPEATIMEVSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPELAEVPTSFFNTTFTNYEMIASENDRVFRFENRI
HRTIVTDQLLLKQLMTILFDNAIKYTEEDGEIDFMISATDRNLYLLVSDNGVGISAEDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALKGSITVKDNKPKGTIFEVKIAIQTPSKKKK
MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDTLHGLSKNPQAVIQLAINRATEEIKDLENAA
TDTSKTEVKPNVSSNTEVILLDKNFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRMILMETNISSVSTN
IKYAAVLINTSQLEQASQKHEQLIVIVMASFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE
TLFRKPEATIMEVSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPELAEVPTSFFNTTFTNYEMIASENDRVFRFENRI
HRTIVTDQLLLKQLMTILFDNAIKYTEEDGEIDFMISATDRNLYLLVSDNGVGISAEDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALKGSITVKDNKPKGTIFEVKIAIQTPSKKKK
Nucleotide
Download Length: 1335 bp
>NTDB_id=75350 UKS_RS03915 WP_156011884.1 757099..758433(+) (ciaH) [Streptococcus sp. 116-D4]
ATGTTCAGTAAACTAAAAAAAACATGGTATGCGGATGACTTTAGTTATTTTATCCGCAATTTTGGTGTCTTCACTCTGAT
TTTCTCTACCATGACCTTGATTATTTTACAGGTCATGCATTCGAGTCTTTATACTTCGGTGGATGATACGCTCCATGGTT
TGAGTAAGAATCCTCAAGCAGTTATTCAGCTTGCTATAAATAGGGCAACAGAAGAGATTAAAGATTTAGAGAATGCCGCT
ACAGATACTAGCAAGACTGAAGTAAAACCCAATGTCAGTTCCAATACGGAGGTTATTCTTTTGGATAAGAATTTTACCCA
ACTACTTTCTGGAAACCGATTTTTGGGATTGGATAAGATTAAGTTAGAGAAAAAAGAACTAGGACATATCTATCAGATTC
AAGTTTTTAATAGCTATGGACAAGAAGAAATCTATCGCATGATTTTGATGGAAACCAATATCAGTTCGGTTTCAACCAAC
ATCAAGTATGCAGCTGTCTTGATTAATACGAGTCAGTTGGAGCAAGCCAGTCAAAAGCATGAGCAATTGATTGTGATTGT
GATGGCAAGTTTCTGGATTCTGTCTTTGCTTGCCAGTCTCTATCTAGCTAGGGTCAGTGTTCGTCCTCTGCTTGAGAGCA
TGCAGAAGCAACAGTCCTTTGTGGAAAATGCCAGTCATGAGTTACGAACTCCACTTGCGGTTTTGCAAAATCGTTTAGAG
ACCCTTTTTCGTAAGCCAGAAGCAACCATTATGGAGGTGAGCGAAAGCATTGCATCAAGTTTGGAAGAAGTCCGAAATAT
GCGGTTTTTGACGACAAACTTGTTGAATTTAGCTCGTAGAGATGATGGAATTAAGCCTGAGCTTGCAGAAGTTCCAACCA
GTTTTTTTAATACGACTTTCACAAACTATGAGATGATTGCTTCTGAAAATGACCGTGTCTTCCGTTTTGAAAATCGGATC
CATCGAACGATTGTCACAGATCAGCTTCTTTTAAAACAACTGATGACCATCCTATTTGATAATGCTATCAAATATACTGA
GGAGGATGGTGAAATTGATTTTATGATTTCAGCGACTGATCGAAATCTGTATTTACTTGTTTCTGATAATGGAGTCGGTA
TTTCCGCAGAAGATAAGAAGAAAATCTTTGATCGATTTTATCGAGTGGATAAGGCCAGAACCCGTCAAAAAGGTGGCTTT
GGTTTAGGTTTATCCCTAGCCAAGCAAATTGTAGATGCCTTAAAAGGAAGCATTACTGTTAAAGATAACAAACCAAAAGG
AACAATCTTTGAAGTGAAGATTGCCATTCAGACACCATCTAAAAAGAAAAAATAA
ATGTTCAGTAAACTAAAAAAAACATGGTATGCGGATGACTTTAGTTATTTTATCCGCAATTTTGGTGTCTTCACTCTGAT
TTTCTCTACCATGACCTTGATTATTTTACAGGTCATGCATTCGAGTCTTTATACTTCGGTGGATGATACGCTCCATGGTT
TGAGTAAGAATCCTCAAGCAGTTATTCAGCTTGCTATAAATAGGGCAACAGAAGAGATTAAAGATTTAGAGAATGCCGCT
ACAGATACTAGCAAGACTGAAGTAAAACCCAATGTCAGTTCCAATACGGAGGTTATTCTTTTGGATAAGAATTTTACCCA
ACTACTTTCTGGAAACCGATTTTTGGGATTGGATAAGATTAAGTTAGAGAAAAAAGAACTAGGACATATCTATCAGATTC
AAGTTTTTAATAGCTATGGACAAGAAGAAATCTATCGCATGATTTTGATGGAAACCAATATCAGTTCGGTTTCAACCAAC
ATCAAGTATGCAGCTGTCTTGATTAATACGAGTCAGTTGGAGCAAGCCAGTCAAAAGCATGAGCAATTGATTGTGATTGT
GATGGCAAGTTTCTGGATTCTGTCTTTGCTTGCCAGTCTCTATCTAGCTAGGGTCAGTGTTCGTCCTCTGCTTGAGAGCA
TGCAGAAGCAACAGTCCTTTGTGGAAAATGCCAGTCATGAGTTACGAACTCCACTTGCGGTTTTGCAAAATCGTTTAGAG
ACCCTTTTTCGTAAGCCAGAAGCAACCATTATGGAGGTGAGCGAAAGCATTGCATCAAGTTTGGAAGAAGTCCGAAATAT
GCGGTTTTTGACGACAAACTTGTTGAATTTAGCTCGTAGAGATGATGGAATTAAGCCTGAGCTTGCAGAAGTTCCAACCA
GTTTTTTTAATACGACTTTCACAAACTATGAGATGATTGCTTCTGAAAATGACCGTGTCTTCCGTTTTGAAAATCGGATC
CATCGAACGATTGTCACAGATCAGCTTCTTTTAAAACAACTGATGACCATCCTATTTGATAATGCTATCAAATATACTGA
GGAGGATGGTGAAATTGATTTTATGATTTCAGCGACTGATCGAAATCTGTATTTACTTGTTTCTGATAATGGAGTCGGTA
TTTCCGCAGAAGATAAGAAGAAAATCTTTGATCGATTTTATCGAGTGGATAAGGCCAGAACCCGTCAAAAAGGTGGCTTT
GGTTTAGGTTTATCCCTAGCCAAGCAAATTGTAGATGCCTTAAAAGGAAGCATTACTGTTAAAGATAACAAACCAAAAGG
AACAATCTTTGAAGTGAAGATTGCCATTCAGACACCATCTAAAAAGAAAAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ciaH | Streptococcus pneumoniae Rx1 |
95.495 |
100 |
0.955 |
| ciaH | Streptococcus pneumoniae D39 |
95.495 |
100 |
0.955 |
| ciaH | Streptococcus pneumoniae R6 |
95.495 |
100 |
0.955 |
| ciaH | Streptococcus pneumoniae TIGR4 |
95.495 |
100 |
0.955 |
| ciaH | Streptococcus mutans UA159 |
55.172 |
97.973 |
0.541 |