Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   OF800_RS02655 Genome accession   NZ_CP109636
Coordinates   516151..516846 (+) Length   231 a.a.
NCBI ID   WP_004259096.1    Uniprot ID   -
Organism   Lactococcus garvieae strain Alexii-6_2     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 511151..521846
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OF800_RS02630 (OF800_02630) - 511384..512085 (+) 702 WP_004259114.1 DeoR/GlpR family DNA-binding transcription regulator -
  OF800_RS02635 (OF800_02635) pfkB 512082..513008 (+) 927 WP_004259111.1 1-phosphofructokinase -
  OF800_RS02640 (OF800_02640) - 513023..514927 (+) 1905 WP_014024348.1 fructose-specific PTS transporter subunit EIIC -
  OF800_RS02645 (OF800_02645) - 515039..515281 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  OF800_RS02650 (OF800_02650) - 515498..516049 (+) 552 WP_165705968.1 YceD family protein -
  OF800_RS02655 (OF800_02655) covR 516151..516846 (+) 696 WP_004259096.1 response regulator transcription factor Regulator
  OF800_RS02660 (OF800_02660) covS 516935..518425 (+) 1491 WP_014024351.1 HAMP domain-containing histidine kinase Regulator
  OF800_RS02665 (OF800_02665) - 518822..520393 (+) 1572 WP_004259090.1 ABC transporter permease subunit -
  OF800_RS02670 (OF800_02670) - 520394..521131 (+) 738 WP_014024353.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26979.74 Da        Isoelectric Point: 5.4730

>NTDB_id=748688 OF800_RS02655 WP_004259096.1 516151..516846(+) (covR) [Lactococcus garvieae strain Alexii-6_2]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQGNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=748688 OF800_RS02655 WP_004259096.1 516151..516846(+) (covR) [Lactococcus garvieae strain Alexii-6_2]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATACCAAACTGCGGTTCAAGGCAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TTGACTTAATGCTCCCAGAGCTTGATGGCTTTGAGGTTGCACGACGCTTACGCCGTGAGAAAGATACACATATTATTATG
ATGACCGCACGTGATTCGACAATGGACCGTGTAGCAGGGCTTGATATTGGTGCAGATGACTATATTACAAAACCATTTGC
TATTGAAGAATTGTTAGCGCGTGTCCGCTCACTCTTCCGTCGTGAAGATCATATCCACACGATTGAAAAGTCAGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAGACCAACCGTACTGTACACCGTGGAAAAAAAGTTATTGACCTTACACGCCGT
GAGTACGATTTGCTTTTGACACTGATGCAAAATGTAGGTGATGTCGTAACACGTGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTGGACGTTTATATCCGTTATCTGCGTAACAAAATTGACGTGGAGGGCCGTG
AAAGCTATATCCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

87.773

99.134

0.87
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424