Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SAGCMC97051_RS04455 Genome accession   NZ_AP020310
Coordinates   794577..795926 (+) Length   449 a.a.
NCBI ID   WP_001065469.1    Uniprot ID   R4ZB13
Organism   Streptococcus agalactiae strain GCMC97051     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 789577..800926
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAGCMC97051_RS04425 (SAGCMC97051_07950) - 790115..790933 (+) 819 WP_000701734.1 ParA family protein -
  SAGCMC97051_RS04430 (SAGCMC97051_07960) - 790933..791211 (+) 279 WP_001282887.1 hypothetical protein -
  SAGCMC97051_RS04435 (SAGCMC97051_07970) - 791223..791618 (+) 396 WP_000323826.1 replication initiator protein A -
  SAGCMC97051_RS04440 (SAGCMC97051_07980) - 791615..791929 (+) 315 WP_000583308.1 hypothetical protein -
  SAGCMC97051_RS04445 (SAGCMC97051_07990) - 792068..793393 (+) 1326 WP_000459145.1 ISLre2 family transposase -
  SAGCMC97051_RS04450 (SAGCMC97051_08000) vicR 793874..794584 (+) 711 WP_000722052.1 response regulator YycF Regulator
  SAGCMC97051_RS04455 (SAGCMC97051_08010) vicK 794577..795926 (+) 1350 WP_001065469.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SAGCMC97051_RS04460 (SAGCMC97051_08020) vicX 795930..796739 (+) 810 WP_001289497.1 MBL fold metallo-hydrolase Regulator
  SAGCMC97051_RS04465 (SAGCMC97051_08030) - 796742..797110 (+) 369 WP_000719384.1 YbaN family protein -
  SAGCMC97051_RS04470 (SAGCMC97051_08040) rnc 797286..797972 (+) 687 WP_000661526.1 ribonuclease III -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51059.13 Da        Isoelectric Point: 4.8621

>NTDB_id=74543 SAGCMC97051_RS04455 WP_001065469.1 794577..795926(+) (vicK) [Streptococcus agalactiae strain GCMC97051]
MNNSAANIRSFELALLFLLVFVAVYFVYLAVRDFKMSKNIRLLNWKVRDLIAGNYSDSILIQGDADLVELGESLNDLSDV
FRMAHDNLEQEKNRLASILTYMTDGVLATDRSGKIVMINETAQQQFNLAYDEALSMNIVDMLGSGSPYSFQDLVSKTPEV
VLNRRDENGEFVTLRIRFALNRRESGFISGLVAVSHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALNE
EVAPSFIKVSLDETNRMMRMISDLLSLSRIDNEVTHLDVEMTNFTAFMTSILNRFDQIRNQKTVTGKVYEIVRDYPLKSI
WVEIDTDKMTQVIDNILNNAVKYSPDGGKITVNLRTTKTQMILSISDQGLGIPKKDLPLIFDRFYRVDKARSRQQGGTGL
GLSIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVTYEEWEDVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=74543 SAGCMC97051_RS04455 WP_001065469.1 794577..795926(+) (vicK) [Streptococcus agalactiae strain GCMC97051]
ATGAATAATAGTGCTGCAAATATTAGGTCGTTTGAGCTAGCCTTACTTTTTTTACTAGTTTTTGTTGCTGTTTATTTTGT
TTATCTAGCGGTTAGAGATTTTAAAATGTCTAAAAATATCCGGCTTTTGAATTGGAAAGTCAGAGATTTGATAGCAGGAA
ATTATTCAGATAGTATTCTAATTCAAGGTGATGCAGATTTAGTAGAATTAGGTGAAAGTCTAAATGATTTATCTGATGTC
TTCCGAATGGCACATGATAACTTAGAACAAGAAAAGAATCGCTTAGCAAGTATCTTAACTTATATGACTGACGGTGTGCT
GGCTACAGATCGTTCAGGAAAAATCGTTATGATTAATGAGACAGCCCAACAGCAGTTCAATCTAGCATATGATGAAGCTT
TATCAATGAATATTGTTGATATGTTAGGGTCGGGAAGTCCATATTCGTTCCAAGATTTAGTCTCTAAAACGCCAGAGGTA
GTTCTTAATAGACGTGATGAAAACGGTGAATTTGTTACCTTACGGATTCGATTTGCTTTGAACCGTCGTGAAAGTGGTTT
TATTTCCGGTTTAGTTGCAGTGTCACACGATGCTACTGAGCAAGAGAAAGAAGAGCGTGAAAGAAGACTTTTTGTATCTA
ATGTTTCTCATGAACTTCGTACACCTTTGACATCTGTAAAATCTTATTTAGAAGCTTTAGATGAGGGAGCGCTTAATGAA
GAAGTTGCTCCAAGCTTCATTAAGGTATCTCTAGATGAAACAAATCGTATGATGCGTATGATATCAGATTTATTAAGTTT
ATCGCGCATTGATAATGAAGTAACGCATTTAGATGTTGAAATGACGAATTTTACAGCTTTCATGACCTCAATTTTGAATC
GATTTGATCAGATTAGAAATCAAAAAACAGTCACAGGAAAAGTTTATGAAATTGTCAGAGATTATCCTCTTAAGTCAATT
TGGGTGGAAATTGATACAGATAAGATGACTCAAGTGATTGATAACATTTTAAATAATGCAGTCAAGTATTCACCAGATGG
TGGTAAGATCACAGTTAATCTACGCACAACTAAAACGCAGATGATTTTATCAATATCAGACCAAGGCTTAGGTATTCCCA
AAAAAGATTTACCTCTCATCTTTGATCGTTTTTATCGTGTTGATAAGGCGAGAAGTCGTCAACAGGGTGGGACTGGACTT
GGTTTGTCAATTGCAAAAGAAATTGTTAAGCAGCATAAGGGATTTATTTGGGCTAAGAGTGAGTATGGTAAAGGGTCTAC
TTTTACAATAGTCTTGCCTTATGATAAAGATGCTGTAACTTATGAAGAATGGGAGGACGTTGAAGATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-180)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB R4ZB13

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.576

91.982

0.686
  micB Streptococcus pneumoniae Cp1015

67.436

96.437

0.65

Multiple sequence alignment