Detailed information NTG0074393

Bioinformatically predicted

Overview

• Name: comQ
• Type: Regulator
• Locus tag: K6K02_RS16940
• Genome accession: NZ_AP024626
• Coordinates: 3223566..3224429 (-)
• Length: 287 a.a.
• NCBI ID: WP_014480705.1
• Uniprot ID: Q9FAF1
• Organism: Bacillus subtilis strain BEST3125
• Function: modification of ComX; production of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 3218566..3229429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6K02_RS16905 (BsBEST3125_32420)	mrpE	3218734..3219210 (+)	477	WP_003228815.1	Na+/H+ antiporter subunit E	-
K6K02_RS16910 (BsBEST3125_32430)	mrpF	3219210..3219494 (+)	285	WP_003228814.1	Na(+)/H(+) antiporter subunit F1	-
K6K02_RS16915 (BsBEST3125_32440)	mnhG	3219478..3219852 (+)	375	WP_014477830.1	monovalent cation/H(+) antiporter subunit G	-
K6K02_RS16920 (BsBEST3125_32450)	yuxO	3219891..3220271 (-)	381	WP_017695528.1	hotdog fold thioesterase	-
K6K02_RS16925 (BsBEST3125_32460)	comA	3220290..3220934 (-)	645	WP_003220716.1	two-component system response regulator ComA	Regulator
K6K02_RS16930 (BsBEST3125_32470)	comP	3221015..3223327 (-)	2313	WP_014480703.1	sensor histidine kinase	Regulator
K6K02_RS16935 (BsBEST3125_32480)	comX	3223343..3223564 (-)	222	WP_014480704.1	competence pheromone ComX	-
K6K02_RS16940 (BsBEST3125_32490)	comQ	3223566..3224429 (-)	864	WP_014480705.1	polyprenyl synthetase family protein	Regulator
K6K02_RS16945 (BsBEST3125_32500)	degQ	3224614..3224754 (-)	141	WP_003220708.1	degradation enzyme regulation protein DegQ	Regulator
K6K02_RS16950	-	3224976..3225101 (+)	126	WP_003228793.1	hypothetical protein	-
K6K02_RS16955 (BsBEST3125_32510)	-	3225215..3225583 (+)	369	WP_014477834.1	hypothetical protein	-
K6K02_RS16960 (BsBEST3125_32520)	pdeH	3225559..3226788 (-)	1230	WP_014480707.1	cyclic di-GMP phosphodiesterase	-
K6K02_RS16965 (BsBEST3125_32530)	pncB	3226924..3228396 (-)	1473	WP_014480708.1	nicotinate phosphoribosyltransferase	-
K6K02_RS16970 (BsBEST3125_32540)	pncA	3228412..3228963 (-)	552	WP_014480709.1	cysteine hydrolase family protein	-

Sequence

Protein

• Length: 287 a.a.
• Molecular weight: 32882.57 Da
• Isoelectric Point: 5.2201

>NTDB_id=74393 K6K02_RS16940 WP_014480705.1 3223566..3224429(-) (comQ) [Bacillus subtilis strain BEST3125]
MKEIVDENILNEDLKVKLISFIKEKKQFSFAELAYYHYIAFDGKNDKAIELLASGIELLILSADIFDDIEDKDNLQASWM
KLDPSIATNAATALYTLSLQVIGSVSNHPKLLSLTLQYSLQSLQGQHVDLNLTASSESEYIEMIKLKSGSLVTLPSILGV
YLATGEYNETVEEYSRYLGIVEQIANDHYGLYYPNYNDFKTRHTLAFNYLKNKFNQSSIDLLNFYAQENHMINNLEDLKG
KLRESGVIQYLNVIKNLAVENFKESFKKLRLDEQRKNKLLIQLLRGI

Nucleotide

• Length: 864 bp

>NTDB_id=74393 K6K02_RS16940 WP_014480705.1 3223566..3224429(-) (comQ) [Bacillus subtilis strain BEST3125]
ATGAAGGAGATTGTGGATGAAAATATTTTAAATGAGGACTTAAAAGTGAAGCTCATTTCTTTTATCAAAGAAAAAAAACA
ATTTTCATTTGCAGAACTGGCTTATTACCATTACATAGCATTTGATGGAAAAAACGACAAAGCAATTGAGTTATTGGCGT
CAGGTATAGAACTTTTAATTTTATCTGCGGACATTTTTGACGATATTGAGGATAAGGACAATCTTCAGGCTTCTTGGATG
AAATTAGATCCTTCTATAGCAACTAACGCAGCTACCGCACTTTATACATTAAGTCTGCAAGTAATAGGTTCAGTCTCAAA
TCATCCAAAACTTTTAAGCCTTACTTTGCAATATTCACTCCAATCTTTACAAGGACAACATGTAGATTTGAATTTAACAG
CCTCATCAGAATCAGAGTATATTGAAATGATTAAACTTAAGTCGGGTTCTCTGGTAACATTGCCCAGTATTCTTGGTGTA
TATCTGGCAACTGGAGAATATAATGAAACAGTTGAGGAGTATTCACGTTATTTAGGTATAGTCGAGCAAATTGCAAATGA
TCACTATGGACTTTATTACCCTAACTATAATGACTTCAAAACTAGACATACGCTTGCCTTCAATTATCTTAAAAATAAAT
TTAACCAATCATCAATTGACTTATTAAATTTTTATGCGCAAGAAAATCATATGATAAATAATTTGGAAGATTTGAAGGGA
AAGTTAAGAGAATCAGGTGTAATACAATATTTGAATGTTATAAAAAATTTAGCAGTGGAAAATTTTAAGGAATCATTCAA
AAAACTGAGATTAGATGAACAAAGAAAAAATAAATTACTTATTCAATTATTAAGGGGGATTTAA

Domains

Predicted by InterProScan.

• Polyprenyl synthetase (polyprenyl_synt) (45-195)

3D structure

• AlphaFold DB: Q9FAF1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comQ	Bacillus subtilis subsp. subtilis str. 168	45	97.561	0.439