Detailed information    

insolico Bioinformatically predicted

Overview

Name   comZ   Type   Machinery gene
Locus tag   AA2Tth_RS06395 Genome accession   NZ_AP019792
Coordinates   1193259..1194935 (+) Length   558 a.a.
NCBI ID   WP_143585829.1    Uniprot ID   -
Organism   Thermus thermophilus strain AA2-20     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1188259..1199935
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA2Tth_RS06370 (TthAA220_12470) - 1189827..1190807 (-) 981 WP_018461695.1 YpdA family putative bacillithiol disulfide reductase -
  AA2Tth_RS06375 (TthAA220_12480) pilA/pilA1 1190973..1191443 (+) 471 WP_143585821.1 GspH/FimT family protein Machinery gene
  AA2Tth_RS06380 (TthAA220_12490) - 1191499..1191972 (+) 474 WP_143585823.1 GspH/FimT family protein -
  AA2Tth_RS06385 (TthAA220_12500) pilA/pilA2 1191990..1192550 (+) 561 WP_242004637.1 type II secretion system protein Machinery gene
  AA2Tth_RS06390 (TthAA220_12510) pilA/pilA3 1192547..1193248 (+) 702 WP_143585827.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  AA2Tth_RS06395 (TthAA220_12520) comZ 1193259..1194935 (+) 1677 WP_143585829.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  AA2Tth_RS06400 (TthAA220_12530) - 1195156..1195506 (+) 351 WP_143585831.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  AA2Tth_RS06410 (TthAA220_12540) - 1195755..1196135 (+) 381 WP_018461702.1 DUF1640 domain-containing protein -
  AA2Tth_RS06415 (TthAA220_12550) - 1196211..1196753 (+) 543 WP_143585835.1 Uma2 family endonuclease -
  AA2Tth_RS06420 (TthAA220_12560) - 1196775..1197539 (-) 765 WP_242004638.1 IS982 family transposase -
  AA2Tth_RS06425 (TthAA220_12570) - 1197626..1198726 (+) 1101 WP_143584933.1 transposase -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 59974.50 Da        Isoelectric Point: 5.6345

>NTDB_id=74049 AA2Tth_RS06395 WP_143585829.1 1193259..1194935(+) (comZ) [Thermus thermophilus strain AA2-20]
MNRKGIALVATLALMVVIALLVFGTFFTTQIELWTTRNDTTSVQAFYAAEAGLQKYKAALFQQYVWREQQGGTGGGSGCF
TSLARGLDLDRDGTLTPFVNNRLVLAQDEVVTDANGNPVGRYTVTLYKDAEDGQLFTLVSEGTSGGAKARVQATFRISNS
DYLEQAIFAGAGQANRWLNGGATIRGGVYVVGSPNDPDQYVIEANGNFALYNWYDLTTYSEVTNRVEPSYRQVQDLCASL
RVQYGKISVGGSTQIGEPNNKVKGVFVGRGAQDITGENVGVCQNNKGVCTEAMGGFDLSDPPPFPTLDAKLDSEACKGYS
TWRACLQGKAALRIQRIGNVLSVASPSDATLPSPCLQAMESGTLTLDTQSVDCTFTRLDGSQGGFRYTYTGDKKSGQGLL
EVFGDVVLEGIDVVLNRPVDYRAQSGSTKSATLAVLKLNGNGGNLDINGNLLPDATFGLFPNHALGFLAEGDIYQRGQYV
MAPLYAGGTFRVVKDNVLFGSVISNQFCTTSAGNQTQCNAGQKAEVVYIRIPKENRPVLLPSLRGGKPVFQVLSYERR

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=74049 AA2Tth_RS06395 WP_143585829.1 1193259..1194935(+) (comZ) [Thermus thermophilus strain AA2-20]
GTGAACCGCAAAGGTATCGCCCTTGTAGCCACTTTGGCCCTCATGGTGGTCATCGCCCTCTTGGTCTTCGGCACCTTCTT
CACCACCCAGATAGAGCTCTGGACCACCCGCAACGACACCACCTCGGTTCAGGCCTTCTACGCCGCTGAGGCCGGCCTGC
AGAAGTACAAGGCCGCCCTCTTCCAGCAGTACGTCTGGCGGGAGCAGCAGGGCGGGACGGGCGGAGGTAGCGGCTGCTTC
ACCTCCCTAGCAAGGGGGCTAGACCTGGACCGGGATGGAACCCTCACCCCCTTCGTCAACAACCGGTTGGTCCTGGCGCA
AGACGAGGTGGTCACCGACGCCAACGGCAACCCCGTGGGGCGGTACACGGTAACCCTTTACAAGGACGCCGAAGACGGCC
AGCTCTTCACCTTGGTCTCCGAGGGCACCTCGGGCGGGGCCAAGGCCCGGGTCCAGGCCACCTTTCGCATCAGCAACTCG
GACTACCTGGAGCAGGCCATCTTCGCCGGCGCGGGCCAGGCGAACAGGTGGCTGAACGGCGGGGCCACCATCCGGGGCGG
GGTCTACGTGGTGGGAAGCCCTAACGACCCGGACCAATACGTCATAGAGGCCAACGGCAACTTTGCCCTCTACAACTGGT
ACGACCTCACCACCTACTCCGAGGTCACCAACCGGGTGGAACCCAGCTACCGGCAGGTCCAGGACCTCTGCGCAAGCCTT
AGGGTGCAGTACGGCAAGATTTCCGTGGGAGGAAGCACCCAGATCGGCGAGCCCAACAACAAGGTGAAGGGGGTCTTCGT
GGGCCGGGGCGCCCAGGACATCACCGGCGAGAACGTGGGGGTCTGCCAGAACAACAAAGGGGTCTGCACCGAGGCCATGG
GGGGCTTTGACCTCTCCGACCCGCCCCCCTTCCCCACCCTGGACGCCAAGCTGGACTCCGAGGCCTGCAAGGGCTACTCC
ACCTGGCGGGCCTGCCTCCAGGGCAAGGCCGCCTTAAGAATCCAGCGCATCGGGAACGTCCTCTCCGTGGCCAGCCCGTC
CGACGCCACCTTGCCCTCACCTTGCCTCCAAGCCATGGAGTCCGGCACCCTGACCCTGGATACCCAAAGCGTGGACTGCA
CCTTCACCCGTCTGGACGGAAGCCAGGGAGGGTTCAGGTACACCTACACGGGCGACAAGAAGAGCGGGCAGGGGCTTTTG
GAAGTCTTCGGCGATGTGGTGCTGGAGGGTATAGACGTGGTGCTCAACCGGCCCGTGGACTATAGGGCCCAGTCGGGGAG
CACCAAGAGCGCCACCCTTGCGGTGCTGAAGCTTAACGGCAACGGCGGCAACCTGGACATCAACGGCAACCTCCTCCCCG
ACGCCACCTTTGGCCTCTTCCCCAACCATGCCCTGGGTTTTCTGGCCGAAGGAGACATCTACCAGCGCGGCCAGTACGTG
ATGGCCCCCCTGTACGCCGGGGGCACCTTCCGGGTGGTGAAGGACAACGTCCTCTTCGGCTCGGTCATTAGCAACCAGTT
CTGCACCACGAGCGCCGGGAACCAAACGCAATGCAACGCCGGCCAAAAGGCCGAGGTGGTCTACATCCGCATCCCCAAGG
AGAACCGCCCCGTGCTCCTGCCGAGCCTCCGCGGGGGGAAGCCCGTCTTCCAGGTGCTCTCCTATGAGCGCCGCTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comZ Thermus thermophilus HB27

92.832

100

0.928

Multiple sequence alignment