Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   QBE57_RS03430 Genome accession   NZ_CP121670
Coordinates   687315..688694 (+) Length   459 a.a.
NCBI ID   WP_012027074.1    Uniprot ID   -
Organism   Streptococcus suis strain HBXY-SL     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 682315..693694
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QBE57_RS03405 pstB 682845..683603 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  QBE57_RS03410 phoU 683632..684288 (+) 657 WP_012028219.1 phosphate signaling complex protein PhoU -
  QBE57_RS03415 - 684490..685692 (-) 1203 WP_012775158.1 IS110 family transposase -
  QBE57_RS03420 - 686077..686457 (+) 381 WP_012027076.1 hypothetical protein -
  QBE57_RS03425 ciaR 686651..687322 (+) 672 WP_009909965.1 response regulator transcription factor Regulator
  QBE57_RS03430 ciaH 687315..688694 (+) 1380 WP_012027074.1 sensor histidine kinase Regulator
  QBE57_RS03435 - 689025..690254 (+) 1230 WP_171935729.1 transglutaminase domain-containing protein -
  QBE57_RS03440 tnpA 690666..691130 (+) 465 WP_012775157.1 IS200/IS605-like element ISSsu4 family transposase -
  QBE57_RS03445 rpsT 691272..691520 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  QBE57_RS03450 coaA 691579..692499 (-) 921 WP_012027068.1 type I pantothenate kinase -
  QBE57_RS03455 - 692608..693198 (+) 591 WP_012027067.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51955.61 Da        Isoelectric Point: 5.5984

>NTDB_id=738557 QBE57_RS03430 WP_012027074.1 687315..688694(+) (ciaH) [Streptococcus suis strain HBXY-SL]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKEQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLANLPLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQIAANIKDKLVCFTVIDNGLGISDV
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=738557 QBE57_RS03430 WP_012027074.1 687315..688694(+) (ciaH) [Streptococcus suis strain HBXY-SL]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGAACAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCAACCTACCGTTAGATAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTAA
CAACGAACTTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGTC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATCTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.237

100

0.492
  ciaH Streptococcus pneumoniae D39

49.237

100

0.492
  ciaH Streptococcus pneumoniae R6

49.237

100

0.492
  ciaH Streptococcus pneumoniae TIGR4

49.237

100

0.492
  ciaH Streptococcus mutans UA159

49.664

97.386

0.484