NTDB

Overview

Name	comGE/cglE	Type	Machinery gene
Locus tag	ODS73_RS10695	Genome accession	NZ_CP107038
Coordinates	2041378..2041680 (-)	Length	100 a.a.
NCBI ID	WP_000413382.1	Uniprot ID	-
Organism	Streptococcus pneumoniae strain BM6001
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2036378..2046680

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ODS73_RS10660 (ODS73_10650)	rnpA	2037057..2037428 (-)	372	WP_000739246.1	ribonuclease P protein component	-
ODS73_RS10665 (ODS73_10655)	-	2037445..2037576 (-)	132	WP_000768904.1	hypothetical protein	-
ODS73_RS10670 (ODS73_10660)	-	2037577..2038767 (-)	1191	WP_284060558.1	acetate kinase	-
ODS73_RS10675 (ODS73_10665)	comYH	2038818..2039771 (-)	954	WP_221015135.1	class I SAM-dependent methyltransferase	Machinery gene
ODS73_RS10680 (ODS73_10670)	-	2039832..2040426 (-)	595	Protein_2091	class I SAM-dependent methyltransferase	-
ODS73_RS10685 (ODS73_10675)	comGG/cglG	2040563..2040976 (-)	414	WP_284060559.1	competence type IV pilus minor pilin ComGG	Machinery gene
ODS73_RS10690 (ODS73_10680)	comGF/cglF	2040954..2041415 (-)	462	WP_000250523.1	competence type IV pilus minor pilin ComGF	Machinery gene
ODS73_RS10695 (ODS73_10685)	comGE/cglE	2041378..2041680 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
ODS73_RS10700 (ODS73_10690)	comGD/cglD	2041643..2042047 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
ODS73_RS10705 (ODS73_10695)	comGC/cglC	2042040..2042306 (-)	267	WP_000962026.1	competence type IV pilus major pilin ComGC	Machinery gene
ODS73_RS10710 (ODS73_10700)	-	2042308..2042565 (-)	258	WP_050266402.1	hypothetical protein	-
ODS73_RS10715 (ODS73_10705)	-	2042795..2043751 (-)	957	WP_284060560.1	N-acetylmuramoyl-L-alanine amidase family protein	-
ODS73_RS10720 (ODS73_10710)	-	2043755..2044087 (-)	333	WP_284060561.1	phage holin	-
ODS73_RS10725 (ODS73_10715)	-	2044091..2044507 (-)	417	WP_000687454.1	phage holin family protein	-
ODS73_RS10730 (ODS73_10720)	-	2044517..2044780 (-)	264	WP_050266966.1	hypothetical protein	-

Sequence

Protein

Download Length: 100 a.a. Molecular weight: 11108.08 Da Isoelectric Point: 9.7273

                                >NTDB_id=737585 ODS73_RS10695 WP_000413382.1 2041378..2041680(-) (comGE/cglE) [Streptococcus pneumoniae strain BM6001]

MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS

SEKGLEVYHGSEQLLAIKEP

Nucleotide

Download Length: 303 bp

                                >NTDB_id=737585 ODS73_RS10695 WP_000413382.1 2041378..2041680(-) (comGE/cglE) [Streptococcus pneumoniae strain BM6001]

ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT

TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG

TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT

AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4

Detailed information NTG0737585